CD209 molecule (Q5204455)

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mammalian protein found in Homo sapiens

DC-SIGN
DC-SIGN1
dendritic cell-specific ICAM-3-grabbing non-integrin 1
HIV gpl20-binding protein
dendritic cell-specific intracellular adhesion molecules (ICAM)-3 grabbing non-integrin
C-type lectin domain family 4 member L
CD209
CD209 antigen
dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin

Language	Label	Description	Also known as
English	CD209 molecule	mammalian protein found in Homo sapiens	DC-SIGN DC-SIGN1 dendritic cell-specific ICAM-3-grabbing non-integrin 1 HIV gpl20-binding protein dendritic cell-specific intracellular adhesion molecules (ICAM)-3 grabbing non-integrin C-type lectin domain family 4 member L CD209 CD209 antigen dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin

Statements

1 reference

13 November 2019

UniProt protein ID

C-type lectin-like/link domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NNX6

C-type lectin fold

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NNX6

C-type lectin-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

CD209-like, C-type lectin-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

C-type lectin, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

peptide antigen binding

determination method

1 reference

8 April 2019

Extensive repertoire of membrane-bound and soluble dendritic cell-specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

virus receptor activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

metal ion binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

protein binding

determination method

3 references

8 April 2019

Interactions of DC-SIGN with Mac-1 and CEACAM1 regulate contact between dendritic cells and neutrophils

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

8 April 2019

DC-SIGN and L-SIGN are high affinity binding receptors for hepatitis C virus glycoprotein E2

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

determination method

1 reference

8 April 2019

Extensive repertoire of membrane-bound and soluble dendritic cell-specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

determination method

1 reference

8 April 2019

Extensive repertoire of membrane-bound and soluble dendritic cell-specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

integral component of membrane

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

extracellular region

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

determination method

1 reference

31 October 2017

Mycobacterium tuberculosis infection of human dendritic cells decreases integrin expression, adhesion and migration to chemokines

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NNX6&geneProductId=UniProtKB:Q9NNX6

determination method

extracellular exosome

determination method

1 reference

31 October 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NNX6&geneProductId=UniProtKB:Q9NNX6

determination method

external side of plasma membrane

determination method

1 reference

8 April 2019

CD4 ligation on human blood monocytes triggers macrophage differentiation and enhances HIV infection

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

plasma membrane

determination method

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

8 April 2019

Dendritic cell-associated lectin-1: a novel dendritic cell-associated, C-type lectin-like molecule enhances T cell secretion of IL-4.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

determination method

1 reference

8 April 2019

Mycobacterium tuberculosis infection of human dendritic cells decreases integrin expression, adhesion and migration to chemokines

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

biological process

leukocyte cell-cell adhesion

determination method

1 reference

8 April 2019

Extensive repertoire of membrane-bound and soluble dendritic cell-specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

cell-cell recognition

determination method

1 reference

8 April 2019

Extensive repertoire of membrane-bound and soluble dendritic cell-specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

intracellular transport of virus

determination method

1 reference

8 April 2019

Extensive repertoire of membrane-bound and soluble dendritic cell-specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

regulation of T cell proliferation

determination method

1 reference

8 April 2019

A mouse C kappa-specific T cell clone indicates that DC-SIGN is an efficient target for antibody-mediated delivery of T cell epitopes for MHC class II presentation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

determination method

1 reference

8 April 2019

Sequence and expression of a membrane-associated C-type lectin that exhibits CD4-independent binding of human immunodeficiency virus envelope glycoprotein gp120

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

intracellular signal transduction

determination method

1 reference

8 April 2019

Extensive repertoire of membrane-bound and soluble dendritic cell-specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

antigen processing and presentation

determination method

1 reference

8 April 2019

Extensive repertoire of membrane-bound and soluble dendritic cell-specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

adaptive immune response

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

immune system process

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

viral genome replication

determination method

1 reference

8 April 2019

Extensive repertoire of membrane-bound and soluble dendritic cell-specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

stimulatory C-type lectin receptor signaling pathway

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

peptide antigen transport

determination method

1 reference

8 April 2019

Extensive repertoire of membrane-bound and soluble dendritic cell-specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

modulation by virus of host process

determination method

1 reference

8 April 2019

Extensive repertoire of membrane-bound and soluble dendritic cell-specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

viral entry into host cell

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

virion attachment to host cell

determination method

1 reference

8 April 2019

Extensive repertoire of membrane-bound and soluble dendritic cell-specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

innate immune response

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

positive regulation of T cell proliferation

determination method

1 reference

8 April 2019

Dendritic cell-associated lectin-1: a novel dendritic cell-associated, C-type lectin-like molecule enhances T cell secretion of IL-4.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

B cell adhesion

determination method

1 reference

8 April 2019

Dendritic cell-associated lectin-1: a novel dendritic cell-associated, C-type lectin-like molecule enhances T cell secretion of IL-4.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNX6

determination method

Gene Atlas image

PBB GE CD209 207277 at fs.png
732 × 530; 10 KB

0 references

C-type lectin-like domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NNX6

C-type lectin, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NNX6

CD209-like, C-type lectin-like domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NNX6

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000204801

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000204801

ENSP00000315407

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000315407

ENSP00000315477

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000315477

ENSP00000346373

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000346373

ENSP00000377716

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000377716

ENSP00000468827

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000468827

ENSP00000470658

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000470658

ENSP00000471137

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000471137

ENSP00000377728

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000377728

ENSP00000470530

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000470530

ENSP00000471348

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000471348

PDB structure ID

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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