Deletion of a silencer element in Igf2 results in loss of imprinting independent of H19. (Q52164786)

26 April 2018

title

Deletion of a silencer element in Igf2 results in loss of imprinting independent of H19. (English)

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26 April 2018

author

Gavin Kelsey

5

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26 April 2018

Wolf Reik

6

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26 April 2018

author name string

Constância M

1

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26 April 2018

Dean W

2

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26 April 2018

Lopes S

3

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26 April 2018

Moore T

4

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26 April 2018

language of work or name

English

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publication date

1 October 2000

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26 April 2018

published in

Nature Genetics

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26 April 2018

volume

26

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26 April 2018

issue

2

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26 April 2018

page(s)

203-206

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26 April 2018

https://scigraph.springernature.com/pub.10.1038/79930

exact match

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cites work

Genomic imprinting in mammals.

1 reference

21 January 2018

Imprinting mechanisms.

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An enhancer deletion affects both H19 and Igf2 expression

21 January 2018

1 reference

Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2.

21 January 2018

1 reference

Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene

21 January 2018

1 reference

CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus

21 January 2018

1 reference

The 5' flank of mouse H19 in an unusual chromatin conformation unidirectionally blocks enhancer-promoter communication

21 January 2018

1 reference

Maternal-specific footprints at putative CTCF sites in the H19 imprinting control region give evidence for insulator function.

21 January 2018

1 reference

Parental imprinting: potentially active chromatin of the repressed maternal allele of the mouse insulin-like growth factor II (Igf2) gene.

21 January 2018

1 reference

Multiple imprinted sense and antisense transcripts, differential methylation and tandem repeats in a putative imprinting control region upstream of mouse Igf2.

21 January 2018

1 reference

Chromatin structure and imprinting: developmental control of DNase-I sensitivity in the mouse insulin-like growth factor 2 gene.

21 January 2018

1 reference

Disruption of imprinting caused by deletion of the H19 gene region in mice

21 January 2018

1 reference

Genomic deletion of an imprint maintenance element abolishes imprinting of both insulin-like growth factor II and H19.

21 January 2018

1 reference

Genomic regions regulating imprinting and insulin-like growth factor-II promoter 3 activity in transgenics: novel enhancer and silencer elements.

21 January 2018

1 reference

Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal.

21 January 2018

1 reference

Structure of the imprinted mouse Snrpn gene and establishment of its parental-specific methylation pattern

21 January 2018

1 reference

Comparative genomic sequencing identifies novel tissue-specific enhancers and sequence elements for methylation-sensitive factors implicated in Igf2/H19 imprinting

21 January 2018

1 reference

Imprinting mutations in the Beckwith-Wiedemann syndrome suggested by altered imprinting pattern in the IGF2-H19 domain.

21 January 2018

1 reference

Imprinting mutation in the Beckwith-Wiedemann syndrome leads to biallelic IGF2 expression through an H19-independent pathway

21 January 2018

1 reference

Imprinting of IGF2 and H19: lack of reciprocity in sporadic Beckwith-Wiedemann syndrome.

21 January 2018

1 reference

21 January 2018

1 reference

Characteristics of imprinted genes

21 January 2018

1 reference

Epigenetic lesions at the H19 locus in Wilms' tumour patients

21 January 2018

1 reference

Loss of imprinting of IGF2 is linked to reduced expression and abnormal methylation of H19 in Wilms' tumour

21 January 2018

1 reference

Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting

21 January 2018

1 reference

The ontogeny of allele-specific methylation associated with imprinted genes in the mouse.

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/79930

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26 April 2018

PubMed ID

11017078

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26 April 2018