Overexpression of the Helix-Loop-Helix protein Id2 blocks T cell development at multiple stages. (Q52174703)

26 April 2018

title

Overexpression of the Helix-Loop-Helix protein Id2 blocks T cell development at multiple stages. (English)

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26 April 2018

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Morrow MA

1

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26 April 2018

Mayer EW

2

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26 April 2018

Perez CA

3

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26 April 2018

Adlam M

4

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26 April 2018

Siu G

5

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26 April 2018

publication date

1 June 1999

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26 April 2018

published in

Molecular Immunology

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26 April 2018

volume

36

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26 April 2018

issue

8

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26 April 2018

page(s)

491-503

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26 April 2018

Delayed thymocyte development induced by augmented expression of p56lck

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E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas

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Id proteins control growth induction in mammalian cells

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The protein Id: a negative regulator of helix-loop-helix DNA binding proteins

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Selecting the T cell receptor repertoire

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A human Id-like helix-loop-helix protein expressed during early development

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Regulation of Id3 cell cycle function by Cdk-2-dependent phosphorylation

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Asymmetric redundancy in CD4 silencer function

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Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family

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Cdk2-dependent phosphorylation of Id2 modulates activity of E2A-related transcription factors

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Two distinct transcription factors that bind the immunoglobulin enhancer microE5/kappa 2 motif

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HEB, a Helix-Loop-Helix Protein Related to E2A and ITF2 That Can Modulate the DNA-Binding Ability of Myogenic Regulatory Factors

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T cell receptor variable gene usage in a specific cytotoxic T cell response. Primary structure of the antigen-MHC receptor of four hapten-specific cytotoxic T cell clones

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Overexpression of Id protein inhibits the muscle differentiation program: in vivo association of Id with E2A proteins

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Helix-loo-helix proteins in the regulation of immunoglobulin gene transcription

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Id gene expression and its suppression by 1,25-dihydroxyvitamin D3 in rat osteoblastic osteosarcoma cells

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Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor

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7 January 2021

Isolation and characterization of bovine and mouse terminal deoxynucleotidyltransferase cDNAs expressible in mammalian cells

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7 January 2021

Inhibition of myeloid differentiation by the helix-loop-helix protein Id

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The molecular genetics of the T-cell antigen receptor and T-cell antigen recognition

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Id2 specifically alters regulation of the cell cycle by tumor suppressor proteins

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Functional activity of myogenic HLH proteins requires hetero-oligomerization with E12/E47-like proteins in vivo

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Regulation of T cell receptor (TCR)-beta locus allelic exclusion and initiation of TCR-alpha locus rearrangement in immature thymocytes by signaling through the CD3 complex

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7 January 2021

Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages

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7 January 2021

RAG-1-deficient mice have no mature B and T lymphocytes

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7 January 2021

Interleukin-7 induces N-myc and c-myc expression in normal precursor B lymphocytes

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7 January 2021

Structure and function of helix-loop-helix proteins

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7 January 2021

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

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7 January 2021

Phosphorylation of helix-loop-helix proteins ID1, ID2 and ID3

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7 January 2021

RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination

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7 January 2021

Multiple rearrangements in T cell receptor alpha chain genes maximize the production of useful thymocytes

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7 January 2021

The expression pattern of Id4, a novel dominant negative helix-loop-helix protein, is distinct from Id1, Id2 and Id3

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7 January 2021

Localization of E2A mRNA expression in developing and adult rat tissues

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7 January 2021

A lineage-specific transcriptional silencer regulates CD4 gene expression during T lymphocyte development

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7 January 2021

The V(D)J recombination activating gene, RAG-1.

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7 January 2021

Selective expression of an antigen receptor on CD8-bearing T lymphocytes in transgenic mice.

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7 January 2021

Positive and negative selection of an antigen receptor on T cells in transgenic mice.

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7 January 2021

Restoration of T cell development in RAG-2-deficient mice by functional TCR transgenes.

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7 January 2021

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

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7 January 2021

A transcriptional silencer controls the developmental expression of the CD4 gene.

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7 January 2021

Constitutive expression of the Id1 gene impairs mouse B cell development

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7 January 2021

Id proteins Id1 and Id2 selectively inhibit DNA binding by one class of helix-loop-helix proteins

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7 January 2021

The myoD Gene Family: Nodal Point During Specification of the Muscle Cell Lineage

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7 January 2021

Muscle-specific transcriptional activation by MyoD

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7 January 2021

Activation of muscle-specific genes in pigment, nerve, fat, liver, and fibroblast cell lines by forced expression of MyoD.

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7 January 2021

Repression of immunoglobulin enhancers by the helix-loop-helix protein Id: implications for B-lymphoid-cell development

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7 January 2021

CD4 expressed on earliest T-lineage precursor cells in the adult murine thymus

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7 January 2021

High incidence of T-cell tumors in E2A-null mice and E2A/Id1 double-knockout mice

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7 January 2021

A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains

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7 January 2021

B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB.

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7 January 2021

Differential expression of myc family genes during murine development

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7 January 2021

10.1016/S0161-5890(99)00071-1

Identifiers

DOI

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26 April 2018

1 reference

26 April 2018