Structure-based methods for predicting mutagenicity and carcinogenicity: are we there yet? (Q52238864)

27 April 2018

review article

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title

Structure-based methods for predicting mutagenicity and carcinogenicity: are we there yet? (English)

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27 April 2018

author name string

Richard AM

series ordinal

1

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27 April 2018

language of work or name

English

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publication date

1 May 1998

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27 April 2018

published in

Mutation Research

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27 April 2018

volume

400

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27 April 2018

issue

1-2

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27 April 2018

page(s)

493-507

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27 April 2018

Carcinogenicity predictions for a group of 30 chemicals undergoing rodent cancer bioassays based on rules derived from subchronic organ toxicities

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Summary and recommendations for session B: activity classification and structure-activity relationship modeling for human health risk assessment of toxic substances

7 January 2021

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International Commission for Protection Against Environmental Mutagens and Carcinogens. Application of SAR methods to non-congeneric data bases associated with carcinogenicity and mutagenicity: issues and approaches

7 January 2021

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Mode of action and the assessment of chemical hazards in the presence of limited data: use of structure-activity relationships (SAR) under TSCA, Section 5

7 January 2021

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Computer Prediction of Possible Toxic Action from Chemical Structure; The DEREK System

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Development of structure-activity relationship rules for predicting carcinogenic potential of chemicals

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Structural relationships between mutagenicity, maximum tolerated dose, and carcinogenicity in rodents.

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Structure-activity and mechanistic relationships: the effect of chemical overlap on structural overlap in data bases of varying size and composition

7 January 2021

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Prediction of the carcinogenicity of a second group of organic chemicals undergoing carcinogenicity testing

7 January 2021

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Species and strain sensitivity to the induction of peroxisome proliferation by chloroacetic acids

7 January 2021

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Failure of monochloroacetic acid and trichloroacetic acid administered in the drinking water to produce liver cancer in male F344/N rats

7 January 2021

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The carcinogenicity of dichloroacetic acid in the male Fischer 344 rat.

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Liver tumor induction in B6C3F1 mice by dichloroacetate and trichloroacetate

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Prediction of the outcome of rodent carcinogenicity bioassays currently being conducted on 44 chemicals by the National Toxicology Program

7 January 2021

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The NIEHS Predictive-Toxicology Evaluation Project

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The first US National Toxicology Program exercise on the prediction of rodent carcinogenicity: definitive results

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Predicting chemical carcinogenesis in rodents

7 January 2021

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10.1016/S0027-5107(98)00068-2

7 January 2021

Identifiers

DOI

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27 April 2018

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27 April 2018