Measurement of the ADP:ATP ratio in human leukaemic cell lines can be used as an indicator of cell viability, necrosis and apoptosis. (Q52539614)

2 May 2018

title

Measurement of the ADP:ATP ratio in human leukaemic cell lines can be used as an indicator of cell viability, necrosis and apoptosis. (English)

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2 May 2018

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Bradbury DA

1

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2 May 2018

Simmons TD

series ordinal

2

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2 May 2018

Slater KJ

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3

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2 May 2018

Crouch SP

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4

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2 May 2018

publication date

1 June 2000

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2 May 2018

Journal of Immunological Methods

published in

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2 May 2018

volume

240

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2 May 2018

issue

1-2

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2 May 2018

page(s)

79-92

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2 May 2018

Commitment to cell death measured by loss of clonogenicity is separable from the appearance of apoptotic markers

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A new method for the cytofluorimetric analysis of mitochondrial membrane potential using the J-aggregate forming lipophilic cation 5,5',6,6'-tetrachloro-1,1',3,3'-tetraethylbenzimidazolcarbocyanine iodide (JC-1).

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Features of apoptotic cells measured by flow cytometry

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Energy metabolism during apoptosis. Bcl-2 promotes survival in hematopoietic cells induced to apoptose by growth factor withdrawal by stabilizing a form of metabolic arrest

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Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

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Chromatin condensation during apoptosis requires ATP.

7 January 2021

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Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

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Mitochondrial control of apoptosis

7 January 2021

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Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis

7 January 2021

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The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy

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Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

7 January 2021

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DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis

7 January 2021

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Mitochondrial membrane potential monitored by JC-1 dye.

7 January 2021

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Control of apoptosis by the cellular ATP level

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JC-1, but not DiOC6(3) or rhodamine 123, is a reliable fluorescent probe to assess delta psi changes in intact cells: implications for studies on mitochondrial functionality during apoptosis

7 January 2021

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Apoptosis and necrosis: intracellular ATP level as a determinant for cell death modes.

7 January 2021

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Chromatin cleavage in apoptosis: association with condensed chromatin morphology and dependence on macromolecular synthesis.

7 January 2021

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Essential role of active nuclear transport in apoptosis

7 January 2021

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Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

7 January 2021

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Methotrexate chemosensitivity by ATP luminescence in human leukemia cell lines and in breast cancer primary cultures: comparison of the TCA-100 assay with a clonogenic assay.

7 January 2021

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7 January 2021

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Identifiers

DOI

10.1016/S0022-1759(00)00178-2

1 reference

2 May 2018

PubMed ID

10854603

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2 May 2018