Kinetics of interaction of disopyramide with the cardiac sodium channel: fast dissociation from open channels at normal rest potentials. (Q52542989)

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25 October 2019

title

Kinetics of interaction of disopyramide with the cardiac sodium channel: fast dissociation from open channels at normal rest potentials (English)

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25 October 2019

4

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25 October 2019

author name string

A O Grant

series ordinal

1

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25 October 2019

D J Wendt

series ordinal

2

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25 October 2019

Y Zilberter

series ordinal

3

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25 October 2019

publication date

1 November 1993

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25 October 2019

number of pages

16

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Journal of Membrane Biology

inferred from page(s)

published in

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25 October 2019

volume

136

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25 October 2019

issue

2

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25 October 2019

page(s)

199-214

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Single sodium channels from canine ventricular myocytes: voltage dependence and relative rates of activation and inactivation.

25 October 2019

cites work

1 reference

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Activation block and trapping of penticainide, a disopyramide analogue, in the Na+ channel of rabbit cardiac Purkinje fibers.

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Stabilization of sodium channel states by deltamethrin in mouse neuroblastoma cells

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Dose-dependent modulation of the cardiac sodium channel by sea anemone toxin ATXII

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Mechanisms of closure of cardiac sodium channels in rabbit ventricular myocytes: single-channel analysis

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The influence of pH on th electrophysiological effects of lidocaine in guinea pig ventricular myocardium

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The activation gate of the sodium channel controls blockade and deblockade by disopyramide in rabbit Purkinje fibres

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Time- and voltage-dependent interactions of antiarrhythmic drugs with cardiac sodium channels

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The charge carried by single-channel currents of rat cultured muscle cells in the presence of local anaesthetics.

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Local anaesthetics transiently block currents through single acetylcholine-receptor channels

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A receptor for type I antiarrhythmic drugs associated with rat cardiac sodium channels

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Two components of use-dependent block of Na+ current by disopyramide and lidocaine in guinea pig ventricular myocytes

21 January 2018

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Effects of quinidine on the sodium current of guinea pig ventricular myocytes. Evidence for a drug-associated rested state with altered kinetics

21 January 2018

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Why do some drugs preferentially block open sodium channels?

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12 December 2020

Molecular and structural basis of resting and use-dependent block of sodium current defined using disopyramide analogues

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12 December 2020

Responsiveness of cardiac Na+ channels to antiarrhythmic drugs: the role of inactivation

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12 December 2020

Sodium current-induced release of calcium from cardiac sarcoplasmic reticulum

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12 December 2020

Sodium channel comodification with full activator reveals veratridine reaction dynamics

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12 December 2020

A source of bias in the analysis of single channel data: assessing the apparent interaction between channel proteins

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12 December 2020

Sodium-calcium exchange in excitable cells: fuzzy space

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12 December 2020

Use-dependent block of cardiac sodium channels by quaternary derivatives of lidocaine

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12 December 2020

Ionic Blockage of Sodium Channels in Nerve

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12 December 2020

Molecular localization of an ion-binding site within the pore of mammalian sodium channels

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12 December 2020

Mechanisms of use-dependent block of sodium channels in excitable membranes by local anesthetics

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12 December 2020

Kinetics of 9-aminoacridine block of single Na channels

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12 December 2020

Sodium inactivation and drug-induced immobilization of the gating charge in nerve membrane

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12 December 2020

Modification of single cardiac Na+ channels by DPI 201-106

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12 December 2020

Disopyramide block of cardiac sodium current after removal of the fast inactivation process in guinea pig ventricular myocytes

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12 December 2020

Phasic ion channel blockade. A kinetic model and parameter estimation procedure.

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Kinetics of local anesthetic inhibition of neuronal sodium currents. pH and hydrophobicity dependence

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12 December 2020

Stereoselective inhibition of neuronal sodium channels by local anesthetics. Evidence for two sites of action?

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Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction

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Modulation of sodium channel gating by external divalent cations: differential effects on opening and closing rates.

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12 December 2020

Local anesthetics. Effect of pH on use-dependent block of sodium channels in frog muscle

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12 December 2020

Negative shift of cardiac Na+ channel kinetics in cell-attached patch recordings

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12 December 2020

Resting and rate-dependent depression of maximum rate of depolarisation (Vmax) in guinea pig ventricular action potentials by mexiletine, disopyramide, and encainide.

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12 December 2020

pH-dependent binding of local anesthetics in single batrachotoxin-activated Na+ channels. Cocaine vs. quaternary compounds

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12 December 2020

Protein binding and erythrocyte partitioning of disopyramide and its monodealkylated metabolite.

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12 December 2020

A reinterpretation of mammalian sodium channel gating based on single channel recording

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12 December 2020

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

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12 December 2020

Kinetic properties of single sodium channels modified by fenvalerate in mouse neuroblastoma cells.

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12 December 2020

Signal discretization: a source of error in histograms of ion channel events.

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

Effect of pKb on Lipophilic Binding of Disopyramide Derivatives to Human Plasma

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12 December 2020

Interactions of flecainide with guinea pig cardiac sodium channels. Importance of activation unblocking to the voltage dependence of recovery

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12 December 2020

Block of activated and inactivated sodium channels by class-I antiarrhythmic drugs studied by using the maximum upstroke velocity (Vmax) of action potential in guinea-pig cardiac muscles

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12 December 2020

Cocaine-induced closures of single batrachotoxin-activated Na+ channels in planar lipid bilayers

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12 December 2020

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12 December 2020

An improved method for isolating cardiac myocytes useful for patch-clamp studies

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12 December 2020

A mutant of TTX-resistant cardiac sodium channels with TTX-sensitive properties

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12 December 2020

Identifiers

DOI

10.1007/BF02505764

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8107074%20AND%20SRC:MED&resulttype=core&format=json

25 October 2019

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