Aberrant expression of pRb, p16, p14ARF, MDM2, p21 and p53 in stage I adenocarcinomas of the lung. (Q52545817)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11940214%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

title

Aberrant expression of pRb, p16, p14ARF, MDM2, p21 and p53 in stage I adenocarcinomas of the lung (English)

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9 December 2019

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2

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9 December 2019

author name string

Qi Xue

1

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9 December 2019

Kenji Kashiwabara

3

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9 December 2019

Masako Saito

4

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9 December 2019

Tetsunari Oyama

5

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9 December 2019

Takashi Nakajima

6

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9 December 2019

publication date

1 February 2002

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9 December 2019

published in

Pathology International

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9 December 2019

volume

52

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9 December 2019

issue

2

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9 December 2019

page(s)

103-109

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A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

9 December 2019

cites work

1 reference

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Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition

21 January 2018

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21 January 2018

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DNA damage-induced activation of p53 by the checkpoint kinase Chk2

21 January 2018

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The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

21 January 2018

1 reference

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The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1827.2002.01321.X

p53: a frequent target for genetic abnormalities in lung cancer.

21 January 2018

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Mutations in the p53 gene occur in diverse human tumour types

21 January 2018

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Abnormalities in structure and expression of the human retinoblastoma gene in SCLC.

21 January 2018

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Alterations of the p16-pRb pathway and the chromosome locus 9p21-22 in non-small-cell lung carcinomas: relationship with p53 and MDM2 protein expression

21 January 2018

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Correlation between methylation status of the p16/CDKN2 gene and the expression of p16 and Rb proteins in primary non-small cell lung cancers.

21 January 2018

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Second primary cancers following breast cancer in the Japanese female population

21 January 2018

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Molecular genetic correlates of p16, cdk4, and pRb immunohistochemistry in glioblastomas

21 January 2018

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Expression status of p16 protein is associated with human papillomavirus oncogenic potential in cervical and genital lesions

21 January 2018

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Prognostic value of the immunohistochemical detection of p16INK4 expression in nonsmall cell lung carcinoma.

21 January 2018

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Cooperative signals governing ARF-mdm2 interaction and nucleolar localization of the complex.

21 January 2018

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21 January 2018

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ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

21 January 2018

1 reference

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Nucleolar Arf sequesters Mdm2 and activates p53

21 January 2018

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The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and down-regulated by wild-type p53.

21 January 2018

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MDM2 gene amplification and expression in non-small-cell lung cancer: immunohistochemical expression of its protein is a favourable prognostic marker in patients without p53 protein accumulation

21 January 2018

1 reference

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Incidence of p14ARF gene deletion in high-grade adult and pediatric astrocytomas.

21 January 2018

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K-ras and p53 mutations are an independent unfavourable prognostic indicator in patients with non-small-cell lung cancer

21 January 2018

1 reference

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10.1046/J.1440-1827.2002.01321.X

21 January 2018

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11940214%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

1 reference