Disruption of dynein/dynactin inhibits axonal transport in motor neurons causing late-onset progressive degeneration. (Q52546347)

3 May 2018

title

Disruption of dynein/dynactin inhibits axonal transport in motor neurons causing late-onset progressive degeneration. (English)

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3 May 2018

9

Erika L F Holzbaur

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author name string

Bernadette H LaMonte

1

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3 May 2018

Karen E Wallace

2

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3 May 2018

Beth A Holloway

3

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3 May 2018

Spencer S Shelly

4

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3 May 2018

Jennifer Ascaño

5

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3 May 2018

Mariko Tokito

6

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3 May 2018

Thomas Van Winkle

7

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3 May 2018

David S Howland

8

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3 May 2018

language of work or name

English

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publication date

1 May 2002

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3 May 2018

published in

Neuron

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3 May 2018

volume

34

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3 May 2018

page(s)

715-727

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3 May 2018

issue

5

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3 May 2018

Cytoplasmic dynein and dynactin are required for the transport of microtubules into the axon

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Transgenic mouse models of Alzheimer's disease and amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

A monoclonal antibody against kinesin inhibits both anterograde and retrograde fast axonal transport in squid axoplasm

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Overexpression of the dynamitin (p50) subunit of the dynactin complex disrupts dynein-dependent maintenance of membrane organelle distribution

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Overexpression of growth-associated proteins in the neurons of adult transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

From Charcot to SOD1: mechanisms of selective motor neuron death in ALS.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Defective axonal transport in a transgenic mouse model of amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Functional analysis of dynactin and cytoplasmic dynein in slow axonal transport.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Molecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Analysis of dynactin subcomplexes reveals a novel actin-related protein associated with the arp1 minifilament pointed end

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Requirement of heavy neurofilament subunit in the development of axons with large calibers

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Absence of the mid-sized neurofilament subunit decreases axonal calibers, levels of light neurofilament (NF-L), and neurofilament content

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Golgi vesiculation and lysosome dispersion in cells lacking cytoplasmic dynein.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Brain dynein (MAP1C) localizes on both anterogradely and retrogradely transported membranous organelles in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Centractin (ARP1) associates with spectrin revealing a potential mechanism to link dynactin to intracellular organelles

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

beta III spectrin binds to the Arp1 subunit of dynactin

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Neurofilaments and motor neuron disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Amyotrophic lateral sclerosis. unfolding the toxicity of the misfolded

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Affinity chromatography demonstrates a direct binding between cytoplasmic dynein and the dynactin complex

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Characterization of the p22 subunit of dynactin reveals the localization of cytoplasmic dynein and dynactin to the midbody of dividing cells

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Dynactin increases the processivity of the cytoplasmic dynein motor

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Cytoplasmic dynein conversion at a crush injury in rat peripheral axons

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Cytoplasmic dynein, the dynactin complex, and kinesin are interdependent and essential for fast axonal transport

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Expression of the p150Glued component of the dynactin complex in developing and adult rat brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Dynactin-Dependent, Dynein-Driven Vesicle Transport in the Absence of Membrane Proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Dynein-dynactin function and sensory axon growth during Drosophila metamorphosis: A role for retrograde motors.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Protein p38: an integral membrane protein specific for small vesicles of neurons and neuroendocrine cells

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Skeletal muscle fatigue and physical endurance of young and old mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Retrograde transport by the microtubule-associated protein MAP 1C.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Evolutionary biology. Pelvic problems for mammals.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Mutant molecular motors disrupt neural circuits in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Bidirectional translocation of neurofilaments along microtubules mediated in part by dynein/dynactin

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

ZW10 helps recruit dynactin and dynein to the kinetochore

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Functionally distinct isoforms of dynactin are expressed in human neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Rapid movement of axonal neurofilaments interrupted by prolonged pauses

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

The p150Glued component of the dynactin complex binds to both microtubules and the actin-related protein centractin (Arp-1)

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

The interaction between cytoplasmic dynein and dynactin is required for fast axonal transport

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Subunit composition of neurofilaments specifies axonal diameter.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Neurofilaments and orthograde transport are reduced in ventral root axons of transgenic mice that express human SOD1 with a G93A mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

Charcot-Marie-Tooth disease type 2A caused by mutation in a microtubule motor KIF1Bbeta

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900696-7

7 January 2021

10.1016/S0896-6273(02)00696-7

Identifiers

DOI

1 reference

3 May 2018

PubMed ID

12062019

1 reference

3 May 2018