High NaCl causes Mre11 to leave the nucleus, disrupting DNA damage signaling and repair. (Q52550084)

3 May 2018

title

High NaCl causes Mre11 to leave the nucleus, disrupting DNA damage signaling and repair. (English)

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3 May 2018

author

Natalia I Dmitrieva

series ordinal

1

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3 May 2018

author name string

Dmitry V Bulavin

series ordinal

2

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3 May 2018

Maurice B Burg

series ordinal

3

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3 May 2018

publication date

8 April 2003

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3 May 2018

American Journal of Physiology - Renal Physiology

published in

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3 May 2018

volume

285

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3 May 2018

issue

2

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3 May 2018

page(s)

F266-74

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3 May 2018

Cell cycle checkpoint signaling through the ATM and ATR kinases

cites work

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00060.2003

Damage recognition in nucleotide excision repair of DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00060.2003

p38 and Chk1 kinases: different conductors for the G(2)/M checkpoint symphony

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00060.2003

Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00060.2003

Phosphorylation activates Chk1 and is required for checkpoint-mediated cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00060.2003

Genomic instability in mice lacking histone H2AX

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00060.2003

Three GADD45 isoforms contribute to hypertonic stress phenotype of murine renal inner medullary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00060.2003

Mre11 protein complex prevents double-strand break accumulation during chromosomal DNA replication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00060.2003

The Mre11 complex: at the crossroads of dna repair and checkpoint signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00060.2003

p53 Protects renal inner medullary cells from hypertonic stress by restricting DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00060.2003

Rapid activation of G2/M checkpoint after hypertonic stress in renal inner medullary epithelial (IME) cells is protective and requires p38 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00060.2003

Renal medullary organic osmolytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00060.2003

Checkpoint activation in response to double-strand breaks requires the Mre11/Rad50/Xrs2 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00060.2003

The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00060.2003

Hyperosmolality in the form of elevated NaCl but not urea causes DNA damage in murine kidney cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00060.2003

Hyperosmolality causes growth arrest of murine kidney cells. Induction of GADD45 and GADD153 by osmosensing via stress-activated protein kinase 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00060.2003

Single-strand interruptions in replicating chromosomes cause double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00060.2003

Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00060.2003

Rapid destruction of human Cdc25A in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00060.2003

Mre11 complex and DNA replication: linkage to E2F and sites of DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00060.2003

hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00060.2003

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00060.2003

An osmotically tolerant inner medullary collecting duct cell line from an SV40 transgenic mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00060.2003

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00060.2003

The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00060.2003

Conditional gene targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00060.2003

Radiosensitization of heat resistant human tumour cells by 1 hour at 41.1 degrees C and its effect on DNA repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00060.2003

BRCA1 regulates the G2/M checkpoint by activating Chk1 kinase upon DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00060.2003

Presence of a calcium-activated chloride current in mouse ventricular myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00060.2003

ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00060.2003

Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00060.2003

The DNA damage response: putting checkpoints in perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00060.2003

Targeted disruption of the Nijmegen breakage syndrome gene NBS1 leads to early embryonic lethality in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00060.2003

10.1152/AJPRENAL.00060.2003

21 January 2018

Identifiers

DOI

1 reference

3 May 2018

PubMed ID

12684226

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3 May 2018