Disruption and aberrant expression of HMGA2 as a consequence of diverse chromosomal translocations in myeloid malignancies. (Q52561913)

3 May 2018

title

Disruption and aberrant expression of HMGA2 as a consequence of diverse chromosomal translocations in myeloid malignancies. (English)

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3 May 2018

author

Nicholas Cross

10

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3 May 2018

author name string

Odero MD

1

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3 May 2018

Grand FH

2

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3 May 2018

Iqbal S

3

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3 May 2018

Ross F

4

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Roman JP

5

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3 May 2018

Vizmanos JL

6

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3 May 2018

Andrieux J

7

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3 May 2018

Laï JL

8

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3 May 2018

Calasanz MJ

9

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3 May 2018

publication date

1 February 2005

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3 May 2018

published in

Leukemia

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3 May 2018

volume

19

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3 May 2018

issue

2

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3 May 2018

page(s)

245-252

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3 May 2018

https://scigraph.springernature.com/pub.10.1038/sj.leu.2403605

exact match

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cites work

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Molecular biology of HMGA proteins: hubs of nuclear function

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Chromatin-associated HMGA and HMGB proteins: versatile co-regulators of DNA-dependent processes

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Regulation of cell-type-specific interleukin-2 receptor alpha-chain gene expression: potential role of physical interactions between Elf-1, HMG-I(Y), and NF-kappa B family proteins

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Functional interaction between the POU domain protein Tst-1/Oct-6 and the high-mobility-group protein HMG-I/Y

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Recurrent rearrangements in the high mobility group protein gene, HMGI-C, in benign mesenchymal tumours

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Analysis of the HMGI nuclear proteins in mouse neoplastic cells induced by different procedures

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Neoplastic transformation of rat thyroid cells requires the junB and fra-1 gene induction which is dependent on the HMGI-C gene product

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Mutation responsible for the mouse pygmy phenotype in the developmentally regulated factor HMGI-C

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Genomic structure and expression of the murine Hmgi-c gene

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LPP, the preferred fusion partner gene of HMGIC in lipomas, is a novel member of the LIM protein gene family

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LHFP, a novel translocation partner gene of HMGIC in a lipoma, is a member of a new family of LHFP-like genes

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Disruption of the architectural factor HMGI-C: DNA-binding AT hook motifs fused in lipomas to distinct transcriptional regulatory domains

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Molecular characterization of a complex chromosomal rearrangement in a pleomorphic salivary gland adenoma involving the 3'-UTR of HMGIC.

21 January 2018

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Identification of NFIB as recurrent translocation partner gene of HMGIC in pleomorphic adenomas

21 January 2018

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Amplification of a rearranged form of the high-mobility group protein gene HMGIC in OsA-CI osteosarcoma cells

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Fusion of a sequence from HEI10 (14q11) to the HMGIC gene at 12q15 in a uterine leiomyoma.

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Dysregulation and overexpression of HMGA2 in myelofibrosis with myeloid metaplasia

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Transgenic mice expressing a truncated form of the high mobility group I-C protein develop adiposity and an abnormally high prevalence of lipomas.

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Truncated and chimeric HMGI-C genes induce neoplastic transformation of NIH3T3 murine fibroblasts

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Overexpression of the HMGA2 gene in transgenic mice leads to the onset of pituitary adenomas

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Molecular dissection of the architectural transcription factor HMGA2

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hREC2, a RAD51-like gene, is disrupted by t(12;14) (q15;q24.1) in a uterine leiomyoma

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Transcriptional activation of the cyclin A gene by the architectural transcription factor HMGA2

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High mobility group A2 protein and its derivatives bind a specific region of the promoter of DNA repair gene ERCC1 and modulate its activity

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In vitro assembly of enhancer complexes

21 January 2018

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7 January 2021

Novel gene fusion of COX6C at 8q22-23 to HMGIC at 12q15 in a uterine leiomyoma

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7 January 2021

HMGA2 is expressed in an allele-specific manner in human lipomas

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7 January 2021

A 12q13 translocation involving the HMGI-C gene in richter transformation of a chronic lymphocytic leukemia

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7 January 2021

The expression of HMGA genes is regulated by their 3'UTR

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7 January 2021

Evidence for RAD51L1/HMGIC fusion in the pathogenesis of uterine leiomyoma

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7 January 2021

HMGA2 expression in uterine leiomyomata and myometrium: quantitative analysis and tissue culture studies

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7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2403605

1 reference

3 May 2018

Dimensions Publication ID

0 references

1 reference

3 May 2018