Disruption of COX-2 modulates gene expression and the cardiac injury response to doxorubicin. (Q52570040)

3 May 2018

title

Disruption of COX-2 modulates gene expression and the cardiac injury response to doxorubicin. (English)

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author

Ryan K. Butler

6

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author name string

Tomas G Neilan

1

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Glen A Doherty

2

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Gang Chen

3

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Catherine Deflandre

4

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Hester McAllister

5

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Sarah E McClelland

7

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Elaine Kay

8

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Leslie R Ballou

9

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Desmond J Fitzgerald

10

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publication date

14 April 2006

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American Journal of Physiology Heart and Circulatory Physiology

published in

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volume

291

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issue

2

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page(s)

H532-6

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Susceptibility of cyclooxygenase-2-deficient mice to pulmonary fibrogenesis

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Cyclooxygenase-2 inhibitor treatment improves left ventricular function and mortality in a murine model of doxorubicin-induced heart failure

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Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II.

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P53-mediated induction of Cox-2 counteracts p53- or genotoxic stress-induced apoptosis

21 January 2018

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Peroxisome proliferator-activated receptor delta activation promotes cell survival following hypertonic stress

21 January 2018

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Dehydration activates an NF-kappaB-driven, COX2-dependent survival mechanism in renal medullary interstitial cells

21 January 2018

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Severity of lung injury in cyclooxygenase-2-deficient mice is dependent on reduced prostaglandin E(2) production.

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Inhibition of cyclooxygenase-2 improves cardiac function after myocardial infarction in the mouse

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Doxorubicin induces apoptosis and CD95 gene expression in human primary endothelial cells through a p53-dependent mechanism.

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Fas-mediated apoptosis in adriamycin-induced cardiomyopathy in rats: In vivo study

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Glycoprotein 130 regulates cardiac myocyte survival in doxorubicin-induced apoptosis through phosphatidylinositol 3-kinase/Akt phosphorylation and Bcl-xL/caspase-3 interaction

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Epirubicin cardiotoxicity: an analysis of 469 patients with metastatic breast cancer

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DRAKs, novel serine/threonine kinases related to death-associated protein kinase that trigger apoptosis

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Probucol protects against adriamycin cardiomyopathy without interfering with its antitumor effect

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Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

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Role of prostaglandin E receptor EP1 subtype in the development of renal injury in genetically hypertensive rats

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Doxorubicin induces apoptosis in normal and tumor cells via distinctly different mechanisms. intermediacy of H(2)O(2)- and p53-dependent pathways

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Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size

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Prostaglandin E2 protects the heart from ischemia-reperfusion injury via its receptor subtype EP4.

21 January 2018

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Activation of peroxisome proliferator-activated receptor-alpha protects the heart from ischemia/reperfusion injury

21 January 2018

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COX-2–Dependent Cardiac Failure in Gh/tTG Transgenic Mice

21 January 2018

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10.1152/AJPHEART.00863.2005

21 January 2018

Identifiers

DOI

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3 May 2018

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3 May 2018