MFN2 agonists reverse mitochondrial defects in preclinical models of Charcot-Marie-Tooth disease type 2A. (Q52576485)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29674596%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

title

MFN2 agonists reverse mitochondrial defects in preclinical models of Charcot-Marie-Tooth disease type 2A (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29674596%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29674596%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

Agostinho G Rocha

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29674596%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

Antonietta Franco

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29674596%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

Andrzej M Krezel

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29674596%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

Nikolaos Biris

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29674596%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

Richard N Kitsis

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29674596%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

Daria Mochly-Rosen

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29674596%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

Evripidis Gavathiotis

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29674596%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

10

Robert H Baloh

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29674596%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

Emmanouil Zacharioudakis

8

object named as

Emmanouil Zacharioudakis

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29674596%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

author name string

Jeanne M Rumsey

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29674596%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

Justin M Alberti

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29674596%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

William C Knight

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29674596%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

R Reid Townsend

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29674596%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

Gerald W Dorn

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29674596%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

language of work or name

English

0 references

publication date

1 April 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29674596%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

number of pages

6

1 reference

inferred from page(s)

published in

Science

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29674596%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

volume

360

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29674596%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

issue

6386

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29674596%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

page(s)

336-341

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29674596%20AND%20SRC:MED&resulttype=core&format=json

Non-radioactive in vitro PINK1 Kinase Assays Using Ubiquitin or Parkin as Substrate

24 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109362

Structures of human mitofusin 1 provide insight into mitochondrial tethering

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109362

Mice Hemizygous for a Pathogenic Mitofusin-2 Allele Exhibit Hind Limb/Foot Gait Deficits and Phenotypic Perturbations in Nerve and Muscle

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109362

Correcting mitochondrial fusion by manipulating mitofusin conformations

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109362

Parkin-mediated mitophagy directs perinatal cardiac metabolic maturation in mice

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109362

Loss of Local Astrocyte Support Disrupts Action Potential Propagation and Glutamate Release Synchrony from Unmyelinated Hippocampal Axon Terminals In Vitro

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109362

A triple-arginine motif in the amino-terminal domain and oligomerization are required for HIV-1 inhibition by human MX2

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109362

Charcot-Marie-Tooth disease type 2A: from typical to rare phenotypic and genotypic features

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109362

PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109362

Structural insights into oligomerization and mitochondrial remodelling of dynamin 1-like protein

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109362

Fusion and fission: interlinked processes critical for mitochondrial health

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109362

Mitofusin2 mutations disrupt axonal mitochondrial positioning and promote axon degeneration

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109362

Structural basis for mechanochemical role of Arabidopsis thaliana dynamin-related protein in membrane fission

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109362

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109362

The crystal structure of dynamin

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109362

Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109362

Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complex

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109362

Phenotypic spectrum of MFN2 mutations in the Spanish population

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109362

Mitochondrial dynamics in mammalian health and disease

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109362

I-TASSER server for protein 3D structure prediction

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109362

Altered axonal mitochondrial transport in the pathogenesis of Charcot-Marie-Tooth disease from mitofusin 2 mutations

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109362

Early onset severe and late-onset mild Charcot-Marie-Tooth disease with mitofusin 2 (MFN2) mutations

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109362

MFN2 mutation distribution and genotype/phenotype correlation in Charcot-Marie-Tooth type 2.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109362

UCSF Chimera--a visualization system for exploratory research and analysis

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109362

Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109362

Patterning of muscle acetylcholine receptor gene expression in the absence of motor innervation

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109362

Mitochondrial abnormalities in Alzheimer's disease.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109362

Clinical and electrophysiologic features of CMT2A with mutations in the mitofusin 2 gene

2 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29674596

12 December 2020

inferred from PubMed ID database lookup

A bacterial dynamin-like protein

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29674596

12 December 2020

inferred from PubMed ID database lookup

Mitochondrial dysfunction in Parkinson's disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29674596

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1126/SCIENCE.AAO1785

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29674596%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29674596%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

PubMed publication ID

29674596

1 reference