Regulation of DNA methylation activity through Dnmt3L promoter methylation by Dnmt3 enzymes in embryonic development. (Q52587407)

4 May 2018

title

Regulation of DNA methylation activity through Dnmt3L promoter methylation by Dnmt3 enzymes in embryonic development. (English)

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4 May 2018

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Ye-Guang Hu

1

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4 May 2018

Ryutaro Hirasawa

2

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4 May 2018

Jia-Lei Hu

3

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4 May 2018

Kenichiro Hata

4

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4 May 2018

Chun-Liang Li

5

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4 May 2018

Ying Jin

6

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4 May 2018

Taiping Chen

7

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4 May 2018

En Li

8

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4 May 2018

Muriel Rigolet

9

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4 May 2018

Evani Viegas-Péquignot

10

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4 May 2018

Hiroyuki Sasaki

11

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4 May 2018

Guo-Liang Xu

12

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4 May 2018

publication date

10 June 2008

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4 May 2018

published in

Human Molecular Genetics

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4 May 2018

volume

17

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4 May 2018

issue

17

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4 May 2018

page(s)

2654-2664

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4 May 2018

The epigenomics of cancer

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Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases

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DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

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Stage-by-stage change in DNA methylation status of Dnmt1 locus during mouse early development.

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A novel Dnmt3a isoform produced from an alternative promoter localizes to euchromatin and its expression correlates with active de novo methylation

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The DNMT3B DNA methyltransferase gene is mutated in the ICF immunodeficiency syndrome

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Isolation and initial characterization of a novel zinc finger gene, DNMT3L, on 21q22.3, related to the cytosine-5-methyltransferase 3 gene family

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Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3L

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Windows for sex-specific methylation marked by DNA methyltransferase expression profiles in mouse germ cells

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Mutations in DNA methyltransferase DNMT3B in ICF syndrome affect its regulation by DNMT3L

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Dnmt3L and the establishment of maternal genomic imprints.

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Role of the Dnmt3 family in de novo methylation of imprinted and repetitive sequences during male germ cell development in the mouse.

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Meiotic and epigenetic defects in Dnmt3L-knockout mouse spermatogenesis.

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Meiotic and epigenetic aberrations in Dnmt3L-deficient male germ cells

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The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a

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DNMT3L stimulates the DNA methylation activity of Dnmt3a and Dnmt3b through a direct interaction

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Mechanism of stimulation of catalytic activity of Dnmt3A and Dnmt3B DNA-(cytosine-C5)-methyltransferases by Dnmt3L.

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Physical and functional interactions between the human DNMT3L protein and members of the de novo methyltransferase family.

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Epigenetic modifications affect Dnmt3L expression

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Use of developmental marker genes to define temporal and spatial patterns of differentiation during embryoid body formation

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Developmental pattern of gene-specific DNA methylation in the mouse embryo and germ line

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Active demethylation of the paternal genome in the mouse zygote

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Dynamic reprogramming of DNA methylation in the early mouse embryo.

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Synergistic function of DNA methyltransferases Dnmt3a and Dnmt3b in the methylation of Oct4 and Nanog

21 January 2018

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Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription

21 January 2018

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Dnmt3a and Dnmt3b are transcriptional repressors that exhibit unique localization properties to heterochromatin

21 January 2018

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Imprinting regulator DNMT3L is a transcriptional repressor associated with histone deacetylase activity

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DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA

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Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation

21 January 2018

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Sex-specific promoters regulate Dnmt3L expression in mouse germ cells.

21 January 2018

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Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing

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DNA methylation profile at the DNMT3L promoter: a potential biomarker for cervical cancer

21 January 2018

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Three novel DNMT3B mutations in Japanese patients with ICF syndrome.

21 January 2018

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Chromatin targeting of de novo DNA methyltransferases by the PWWP domain

21 January 2018

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Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b.

21 January 2018

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Transition in cardiac contractile sensitivity to calcium during the in vitro differentiation of mouse embryonic stem cells

21 January 2018

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Quantification of mRNA using real-time reverse transcription PCR (RT-PCR): trends and problems.

21 January 2018

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Stat4 limits DNA methyltransferase recruitment and DNA methylation of the IL-18Ralpha gene during Th1 differentiation

21 January 2018

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Growing Y-junction carbon nanotubes

21 January 2018

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Demethylation of the zygotic paternal genome

21 January 2018

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21 January 2018

Identifiers

DOI

10.1093/HMG/DDN165

1 reference

4 May 2018

PubMed ID

18544626

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4 May 2018