The p35 relative, p49, inhibits mammalian and Drosophila caspases including DRONC and protects against apoptosis. (Q52601635)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12478468%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

title

The p35 relative, p49, inhibits mammalian and Drosophila caspases including DRONC and protects against apoptosis (English)

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15 December 2019

2

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15 December 2019

Elizabeth J. Coulson

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15 December 2019

Anissa M Jabbour

1

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15 December 2019

Christine Hawkins

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15 December 2019

author name string

M J Knight

4

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15 December 2019

D M Ashley

5

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15 December 2019

publication date

1 December 2002

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Cell Death & Differentiation

15 December 2019

published in

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15 December 2019

volume

9

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15 December 2019

issue

12

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15 December 2019

page(s)

1311-1320

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https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401135

15 December 2019

exact match

0 references

cites work

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21 January 2018

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Homologous p35 proteins of baculoviruses show distinctive anti-apoptotic activities which correlate with the apoptosis-inducing activity of each virus

21 January 2018

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Inhibition of the Caenorhabditis elegans cell-death protease CED-3 by a CED-3 cleavage site in baculovirus p35 protein

21 January 2018

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Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35.

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Crystal structure of baculovirus P35: role of a novel reactive site loop in apoptotic caspase inhibition

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Mechanism-based inactivation of caspases by the apoptotic suppressor p35.

21 January 2018

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Crystal structure of baculovirus P35 reveals a novel conformational change in the reactive site loop after caspase cleavage

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Covalent inhibition revealed by the crystal structure of the caspase-8/p35 complex

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Caspase inhibition by baculovirus P35 requires interaction between the reactive site loop and the beta-sheet core

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The Drosophila caspase DRONC is regulated by DIAP1

21 January 2018

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Caspase inhibitor P35 and inhibitor of apoptosis Op-IAP block in vivo proteolytic activation of an effector caspase at different steps

21 January 2018

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Baculovirus P35 protein does not inhibit caspase-9 in a cell-free system of apoptosis

21 January 2018

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Inhibitor specificity of recombinant and endogenous caspase-9.

21 January 2018

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Apoptosis in motion. An apical, P35-insensitive caspase mediates programmed cell death in insect cells

21 January 2018

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A cloning method to identify caspases and their regulators in yeast: identification of Drosophila IAP1 as an inhibitor of the Drosophila caspase DCP-1.

21 January 2018

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X-linked IAP is a direct inhibitor of cell-death proteases

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Analysis of FasL and TRAIL induced apoptosis pathways in glioma cells.

21 January 2018

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Direct inhibition of caspase 3 is dispensable for the anti-apoptotic activity of XIAP.

21 January 2018

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DRONC, an ecdysone-inducible Drosophila caspase

21 January 2018

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Expression of the baculovirus p35 gene inhibits mammalian neural cell death

21 January 2018

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The baculovirus p35 protein inhibits Fas- and tumor necrosis factor-induced apoptosis.

21 January 2018

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Viral proteins E1B19K and p35 protect sympathetic neurons from cell death induced by NGF deprivation

21 January 2018

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Blocked negative selection of developing T cells in mice expressing the baculovirus p35 caspase inhibitor.

21 January 2018

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Caspases determine the vulnerability of oligodendrocytes in the ischemic brain

21 January 2018

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Targeted expression of baculovirus p35 caspase inhibitor in oligodendrocytes protects mice against autoimmune-mediated demyelination

21 January 2018

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Transgenic mice neuronally expressing baculoviral p35 are resistant to diverse types of induced apoptosis, including seizure-associated neurodegeneration

21 January 2018

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Caspase enzyme activity is not essential for apoptosis during thymocyte development

21 January 2018

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21 January 2018

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21 January 2018

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Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3

21 January 2018

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Regulation of apoptosis by viral gene products

21 January 2018

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7 January 2021

Apoptotic suppression by baculovirus P35 involves cleavage by and inhibition of a virus-induced CED-3/ICE-like protease

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7 January 2021

Isolation of an apoptosis suppressor gene of the Spodoptera littoralis nucleopolyhedrovirus

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7 January 2021

Analysis of candidate antagonists of IAP-mediated caspase inhibition using yeast reconstituted with the mammalian Apaf-1-activated apoptosis mechanism

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7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4401135

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12478468%20AND%20SRC:MED&resulttype=core&format=json

release_2mxjwz32jzf4pcchvsd4zyhjra

15 December 2019

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/2mxjwz32jzf4pcchvsd4zyhjra

24 November 2022

mapped directly with Wikidata item

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