Design, synthesis and biological evaluation of non-natural modulators of quorum sensing in Pseudomonas aeruginosa. (Q52624251)

4 May 2018

title

Design, synthesis and biological evaluation of non-natural modulators of quorum sensing in Pseudomonas aeruginosa. (English)

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4 May 2018

main subject

quorum sensing

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Pseudomonas aeruginosa

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author

David R. Spring

7

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4 May 2018

Megan H Wright

Megan Wright

3

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James T Hodgkinson

James T Hodgkinson

1

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Martin Welch

6

Martin Welch

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4 May 2018

Rebecca Nicholson

5

Rebecca L Nicholson

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4 May 2018

author name string

Warren R J D Galloway

2

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4 May 2018

Ioulia K Mati

4

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4 May 2018

publication date

13 April 2012

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4 May 2018

Organic and Biomolecular Chemistry

published in

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4 May 2018

volume

10

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4 May 2018

issue

30

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4 May 2018

page(s)

6032-6044

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4 May 2018

Quorum sensing in Gram-negative bacteria: small-molecule modulation of AHL and AI-2 quorum sensing pathways

cites work

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Structural basis of acyl-homoserine lactone-dependent signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Mechanisms and synthetic modulators of AHL-dependent gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Quorum sensing and social networking in the microbial world.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Quorum sensing in bacteria: the LuxR-LuxI family of cell density-responsive transcriptional regulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Regulation of gene expression by cell-to-cell communication: acyl-homoserine lactone quorum sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Cell-cell signalling in bacteria: not simply a matter of quorum

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Design, synthesis, and biological evaluation of abiotic, non-lactone modulators of LuxR-type quorum sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Efficient synthesis and evaluation of quorum-sensing modulators using small molecule macroarrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Messing with bacterial quorum sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Quorum sensing, communication and cross-kingdom signalling in the bacterial world.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Look who's talking: communication and quorum sensing in the bacterial world.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Quorum-sensing regulation in rhizobia and its role in symbiotic interactions with legumes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Expanding dialogues: from natural autoinducers to non-natural analogues that modulate quorum sensing in Gram-negative bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Modulation of bacterial quorum sensing with synthetic ligands: systematic evaluation of N-acylated homoserine lactones in multiple species and new insights into their mechanisms of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Learning the language of bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Bacterial quorum-sensing network architectures

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

The social behaviours of bacterial pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

The Pseudomonas aeruginosa quinolone signal molecule overcomes the cell density-dependency of the quorum sensing hierarchy, regulates rhl-dependent genes at the onset of stationary phase and can be produced in the absence of LasR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Structure-activity analysis of the Pseudomonas quinolone signal molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Treatment of Pseudomonas aeruginosa infection in critically ill patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Induction and inhibition of Pseudomonas aeruginosa quorum sensing by synthetic autoinducer analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

PA2663 (PpyR) increases biofilm formation in Pseudomonas aeruginosa PAO1 through the psl operon and stimulates virulence and quorum-sensing phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

4-quinolone signalling in Pseudomonas aeruginosa: old molecules, new perspectives.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Structural understanding of quorum-sensing inhibitors by molecular modeling study in Pseudomonas aeruginosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Effects of antibiotics on quorum sensing in Pseudomonas aeruginosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Inhibition of quorum sensing in Pseudomonas aeruginosa biofilm bacteria by a halogenated furanone compound.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Revisiting the quorum-sensing hierarchy in Pseudomonas aeruginosa: the transcriptional regulator RhlR regulates LasR-specific factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Quorum sensing inhibitors: a bargain of effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Synthesis of multiple exoproducts in Pseudomonas aeruginosa is under the control of RhlR-RhlI, another set of regulators in strain PAO1 with homology to the autoinducer-responsive LuxR-LuxI family

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Synthetic furanones inhibit quorum-sensing and enhance bacterial clearance in Pseudomonas aeruginosa lung infection in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Multidrug-resistant Gram-negative bacteria: how to treat and for how long

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Library screening for synthetic agonists and antagonists of a Pseudomonas aeruginosa autoinducer

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Discovery of a quorum sensing modulator pharmacophore by 3D small-molecule microarray screening.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

2-Methoxycyclopentyl analogues of a Pseudomonas aeruginosa quorum sensing modulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Synthesis and stability of small molecule probes for Pseudomonas aeruginosa quorum sensing modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Small molecule inhibitors of bacterial quorum sensing and biofilm formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Synthetic homoserine lactone-derived sulfonylureas as inhibitors of Vibrio fischeri quorum sensing regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Covalent inhibition of bacterial quorum sensing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Roles of Pseudomonas aeruginosa las and rhl quorum-sensing systems in control of elastase and rhamnolipid biosynthesis genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

The role of pyocyanin in Pseudomonas aeruginosa infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Identification and characterization of genes for a second anthranilate synthase in Pseudomonas aeruginosa: interchangeability of the two anthranilate synthases and evolutionary implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Novel Pseudomonas aeruginosa quorum-sensing inhibitors identified in an ultra-high-throughput screen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Mastering the chemical language of bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Microwave and flow syntheses of Pseudomonasquinolone signal (PQS) and analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

Robust routes for the synthesis of N-acylated-l-homoserine lactone (AHL) quorum sensing molecules with high levels of enantiomeric purity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2OB25198A

21 January 2018

Identifiers

DOI

10.1039/C2OB25198A

1 reference

4 May 2018

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4 May 2018