A vaccine platform against arenaviruses based on a recombinant hyper-attenuated Mopeia virus expressing heterologous glycoproteins. (Q52625005)

4 May 2018

title

A vaccine platform against arenaviruses based on a recombinant hyper-attenuated Mopeia virus expressing heterologous glycoproteins. (English)

1 reference

4 May 2018

1 reference

Stéphanie Reynard

4

0 references

Xavier Carnec

Xavier Carnec

1

0 references

Mathieu Mateo

Mathieu Matéo

2

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François Ferron

François Ferron

8

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Sylvain Baize

Sylvain Baize

9

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author name string

Audrey Page

3

1 reference

4 May 2018

Jimmy Hortion

5

1 reference

4 May 2018

Caroline Picard

6

1 reference

4 May 2018

Elsie Yekwa

7

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4 May 2018

language of work or name

English

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publication date

28 March 2018

1 reference

4 May 2018

published in

Journal of Virology

1 reference

4 May 2018

Activity inhibition and crystal polymorphism induced by active-site metal swapping

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Differences in Glycoprotein Complex Receptor Binding Site Accessibility Prompt Poor Cross-Reactivity of Neutralizing Antibodies between Closely Related Arenaviruses.

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Development of live-attenuated arenavirus vaccines based on codon deoptimization of the viral glycoprotein.

2 November 2018

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Activation of the RLR/MAVS Signaling Pathway by the L Protein of Mopeia Virus

2 November 2018

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Evidence of human infection by a new mammarenavirus endemic to Southeastern Asia

2 November 2018

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Monoclonal antibody therapy for Junin virus infection

2 November 2018

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Glycoprotein-Specific Antibodies Produced by DNA Vaccination Protect Guinea Pigs from Lethal Argentine and Venezuelan Hemorrhagic Fever

2 November 2018

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The High Degree of Sequence Plasticity of the Arenavirus Noncoding Intergenic Region (IGR) Enables the Use of a Nonviral Universal Synthetic IGR To Attenuate Arenaviruses

2 November 2018

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Molecular Basis for Antibody-Mediated Neutralization of New World Hemorrhagic Fever Mammarenaviruses

2 November 2018

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General Molecular Strategy for Development of Arenavirus Live-Attenuated Vaccines

2 November 2018

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Clinical Sequencing Uncovers Origins and Evolution of Lassa Virus

2 November 2018

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Arenavirus Genome Rearrangement for the Development of Live Attenuated Vaccines

2 November 2018

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A recombinant vesicular stomatitis virus-based Lassa fever vaccine protects guinea pigs and macaques against challenge with geographically and genetically distinct Lassa viruses

2 November 2018

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A Recombinant Vesicular Stomatitis Virus Ebola Vaccine — Preliminary Report

2 November 2018

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The glycoprotein precursor gene of Junin virus determines the virulence of the Romero strain and the attenuation of the Candid #1 strain in a representative animal model of Argentine hemorrhagic fever

2 November 2018

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Development of live-attenuated arenavirus vaccines based on codon deoptimization

2 November 2018

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Gairo virus, a novel arenavirus of the widespread Mastomys natalensis: Genetically divergent, but ecologically similar to Lassa and Morogoro viruses

2 November 2018

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The Z proteins of pathogenic but not nonpathogenic arenaviruses inhibit RIG-I-like receptor-dependent interferon production

2 November 2018

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Exonuclease domain of the Lassa virus nucleoprotein is critical to avoid RIG-I signaling and to inhibit the innate immune response

2 November 2018

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Infection of type I interferon receptor-deficient mice with various old world arenaviruses: a model for studying virulence and host species barriers

2 November 2018

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An attenuated Lassa vaccine in SIV-infected rhesus macaques does not persist or cause arenavirus disease but does elicit Lassa virus-specific immunity.

2 November 2018

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Characterization of virulence-associated determinants in the envelope glycoprotein of Pichinde virus

2 November 2018

1 reference

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Arenavirus nucleoprotein targets interferon regulatory factor-activating kinase IKKε.

2 November 2018

1 reference

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Lassa virus nucleoprotein mutants generated by reverse genetics induce a robust type I interferon response in human dendritic cells and macrophages

2 November 2018

1 reference

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The major determinant of attenuation in mice of the Candid1 vaccine for Argentine hemorrhagic fever is located in the G2 glycoprotein transmembrane domain

2 November 2018

1 reference

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Human dendritic cells infected with the nonpathogenic Mopeia virus induce stronger T-cell responses than those infected with Lassa virus

2 November 2018

1 reference

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Cap binding and immune evasion revealed by Lassa nucleoprotein structure

2 November 2018

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Induction and inhibition of type I interferon responses by distinct components of lymphocytic choriomeningitis virus

2 November 2018

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Safety, immunogenicity, and efficacy of the ML29 reassortant vaccine for Lassa fever in small non-human primates

2 November 2018

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Inhibition of the type I interferon response by the nucleoprotein of the prototypic arenavirus lymphocytic choriomeningitis virus

2 November 2018

1 reference

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Envelope exchange for the generation of live-attenuated arenavirus vaccines

2 November 2018

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Role of interferons in the control of Lassa virus replication in human dendritic cells and macrophages.

2 November 2018

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A live attenuated vaccine for Lassa fever made by reassortment of Lassa and Mopeia viruses

2 November 2018

1 reference

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Development of a new vaccine for the prevention of Lassa fever

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5974477

Human macrophages, but not dendritic cells, are activated and produce alpha/beta interferons in response to Mopeia virus infection

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5974477

Lassa virus infection of human dendritic cells and macrophages is productive but fails to activate cells

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5974477

Effective vaccine for lassa fever

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5974477

Experimental Infection of Rhesus Monkeys with Lassa Virus and a Closely Related Arenavirus, Mozambique Virus

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5974477

A prospective study of the epidemiology and ecology of Lassa fever

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5974477

Protection of rhesus monkeys from fatal Lassa fever by vaccination with a recombinant vaccinia virus containing the Lassa virus glycoprotein gene

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5974477

Acute sensorineural deafness in Lassa fever

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5974477

Generation of reassortants between African arenaviruses

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5974477

Isolation of an arenavirus closely related to Lassa virus from Mastomys natalensis in south-east Africa

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5974477

Protection of rhesus monkeys from Lassa virus by immunisation with closely related Arenavirus

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5974477

2 November 2018

Identifiers

DOI

10.1128/JVI.02230-17

1 reference

4 May 2018

PMC publication ID

5974477

0 references

1 reference

4 May 2018