Derlin 2 (Q5262654)

mammalian protein found in Homo sapiens

DERtrin-2
DERL2
Der1-like domain family, member 2
carcinoma related
F-LAN-1
degradation in endoplasmic reticulum protein 2
F-LANa
Der1-like protein 2
derlin-2

Language	Label	Description	Also known as
English	Derlin 2	mammalian protein found in Homo sapiens	DERtrin-2 DERL2 Der1-like domain family, member 2 carcinoma related F-LAN-1 degradation in endoplasmic reticulum protein 2 F-LANa Der1-like protein 2 derlin-2

Statements

1 reference

13 November 2019

1 reference

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9GZP9

Endoplasmic Reticular Retrotranslocon

0 references

1 reference

13 November 2019

1 reference

13 November 2019

integral component of membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZP9

determination method

IEA

integral component of endoplasmic reticulum membrane

1 reference

8 April 2019

Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZP9

1 reference

8 April 2019

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZP9

1 reference

8 April 2019

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZP9

determination method

IEA

endoplasmic reticulum

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZP9

8 April 2019

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZP9

8 April 2019

A membrane protein required for dislocation of misfolded proteins from the ER

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZP9

determination method

IDA

endoplasmic reticulum quality control compartment

1 reference

8 April 2019

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZP9

determination method

IEA

signal recognition particle receptor complex

1 reference

8 April 2019

Pre-emptive Quality Control Protects the ER from Protein Overload via the Proximity of ERAD Components and SRP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZP9

determination method

IDA

signal recognition particle

1 reference

8 April 2019

Pre-emptive Quality Control Protects the ER from Protein Overload via the Proximity of ERAD Components and SRP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZP9

determination method

IDA

biological process

endoplasmic reticulum unfolded protein response

1 reference

8 April 2019

Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZP9

determination method

IDA

positive regulation of cell growth

1 reference

8 April 2019

Cloning and characterization of F-LANa, upregulated in human liver cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZP9

determination method

IDA

response to unfolded protein

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZP9

determination method

IEA

negative regulation of retrograde protein transport, ER to cytosol

1 reference

8 April 2019

Identification of ERAD components essential for dislocation of the null Hong Kong variant of α-1-antitrypsin (NHK)

GOA

curator

Parkinsons Disease Gene Ontology Initiative

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZP9

determination method

IMP

positive regulation of cell population proliferation

1 reference

8 April 2019

Cloning and characterization of F-LANa, upregulated in human liver cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZP9

determination method

IDA

ubiquitin-dependent ERAD pathway

1 reference

8 April 2019

Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZP9

1 reference

8 April 2019

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZP9

determination method

IEA

endoplasmic reticulum mannose trimming

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZP9

determination method

TAS

Gene Atlas image

PBB GE DERL2 218333 at fs.png
732 × 530; 11 KB

0 references

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

Transporter Classification Database ID

3.A.16.1.4

2 references

stated in

Transporter Classification database

retrieved

13 March 2020

stated in

Transporter Classification database

retrieved

29 April 2020

Derlin 2 (Q5262654)

Statements

Identifiers

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Derlin 2 (Q5262654)

Statements

Identifiers

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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