Desert hedgehog signaling molecule (Q5264074)

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mammalian protein found in Homo sapiens

• DHH
• desert hedgehog protein
• HHG-3

edit

Language	Label	Description	Also known as
English	Desert hedgehog signaling molecule	mammalian protein found in Homo sapiens	DHH desert hedgehog protein HHG-3

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

O43323

part of

Hedgehog signalling/DD-peptidase zinc-binding domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O43323

Hint domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O43323

hedgehog protein

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O43323

Hint domain N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Hint domain C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Hedgehog protein, Hint domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Hedgehog, N-terminal signalling domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

O43323

encoded by

DHH

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

O43323

molecular function

calcium ion binding

determination method

IDA

1 reference

retrieved

1 January 2018

stated in

Structural insights into hedgehog ligand sequestration by the human hedgehog-interacting protein HHIP

GOA

curator

UniProt

UniProt protein ID

O43323

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IDA

zinc ion binding

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

Structural insights into hedgehog ligand sequestration by the human hedgehog-interacting protein HHIP

GOA

curator

UniProt

UniProt protein ID

O43323

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IDA

metal ion binding

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O43323

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IEA

patched binding

determination method

IEA

1 reference

retrieved

16 July 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43323&geneProductId=UniProtKB:O43323

determination method

IEA

peptidase activity

determination method

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O43323

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IEA

protein binding

determination method

IPI

3 references

retrieved

8 April 2019

stated in

Structural insights into hedgehog ligand sequestration by the human hedgehog-interacting protein HHIP

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IPI

retrieved

8 April 2019

stated in

All Mammalian Hedgehog Proteins Interact with Cell Adhesion Molecule, Down-regulated by Oncogenes (CDO) and Brother of CDO (BOC) in a Conserved Manner

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IPI

retrieved

8 April 2019

stated in

Structural insights into hedgehog ligand sequestration by the human hedgehog-interacting protein HHIP

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IPI

hydrolase activity

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O43323

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IEA

patched binding

determination method

IBA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IBA

calcium ion binding

determination method

IBA

IDA

2 references

retrieved

8 April 2019

stated in

Structural insights into hedgehog ligand sequestration by the human hedgehog-interacting protein HHIP

GOA

curator

UniProt

UniProt protein ID

O43323

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IBA

cell component

membrane

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O43323

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IEA

plasma membrane

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O43323

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IEA

extracellular region

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O43323

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IEA

extracellular space

determination method

IEA

1 reference

retrieved

1 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

O43323

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IEA

extracellular space

determination method

IBA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O43323

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IBA

biological process

response to estradiol

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IEA

Leydig cell differentiation

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IEA

cell-cell signaling

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IEA

regulation of steroid biosynthetic process

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IEA

male sex determination

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IEA

proteolysis

determination method

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O43323

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IEA

response to estrogen

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IEA

multicellular organism development

determination method

IEA

3 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O43323

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IEA

spermatid development

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IEA

myelination

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IEA

osteoblast differentiation

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IEA

smoothened signaling pathway

determination method

IEA

1 reference

retrieved

16 July 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43323&geneProductId=UniProtKB:O43323

determination method

IEA

cell fate specification

determination method

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IBA

smoothened signaling pathway

determination method

IBA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IBA

regulation of gene expression

determination method

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43323

determination method

IBA

Gene Atlas image

PBB GE DHH gnf1h08867 at fs.png
732 × 530; 11 KB

0 references

has part(s)

Hint domain C-terminal

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O43323

Hint domain N-terminal

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O43323

Hedgehog, N-terminal signalling domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O43323

Hedgehog protein, Hint domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O43323

Identifiers

RefSeq protein ID

NP_066382

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

50846

XP_016874869

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

50846

XP_016874870

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

50846

UniProt protein ID

O43323

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

O43323

BabelNet ID

00701251n

1 reference

stated in

BabelNet

Ensembl protein ID

ENSP00000497483

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000497483

PDB structure ID

2WFQ

1 reference

stated in

UniProt

UniProt protein ID

O43323

retrieved

29 June 2016

language of work or name

English

2WFR

1 reference

stated in

UniProt

UniProt protein ID

O43323

retrieved

29 June 2016

language of work or name

English

2WG3

1 reference

stated in

UniProt

UniProt protein ID

O43323

retrieved

29 June 2016

language of work or name

English

3N1G

1 reference

stated in

UniProt

UniProt protein ID

O43323

retrieved

29 June 2016

language of work or name

English

3N1Q

1 reference

stated in

UniProt

UniProt protein ID

O43323

retrieved

29 June 2016

language of work or name

English

 

Sitelinks

Wikipedia(1 entry)

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• enwiki Desert hedgehog protein

Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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Retrieved from "https://www.wikidata.org/w/index.php?title=Q5264074&oldid=2022907409"