A humanized anti-human CD154 monoclonal antibody blocks CD154-CD40 mediated human B cell activation. (Q52843789)

8 May 2018

title

A humanized anti-human CD154 monoclonal antibody blocks CD154-CD40 mediated human B cell activation. (English)

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8 May 2018

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Brams P

1

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8 May 2018

Black A

2

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8 May 2018

Padlan EA

3

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8 May 2018

Hariharan K

4

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8 May 2018

Leonard J

5

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8 May 2018

Chambers-Slater K

6

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8 May 2018

Noelle RJ

7

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8 May 2018

Newman R

8

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8 May 2018

publication date

1 February 2001

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8 May 2018

International Immunopharmacology

published in

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8 May 2018

volume

1

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8 May 2018

page(s)

277-294

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8 May 2018

issue

2

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8 May 2018

CD40 and its ligand, an essential ligand-receptor pair for thymus-dependent B-cell activation

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A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells

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Long-Term Human B Cell Lines Dependent on Interleukin-4 and antibody to CD40

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Activated T cells induce expression of B7/BB1 on normal or leukemic B cells through a CD40-dependent signal

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Activated human B lymphocytes express three CTLA-4 counterreceptors that costimulate T-cell activation

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Arrest of B lymphocyte terminal differentiation by CD40 signaling: mechanism for lack of antibody-secreting cells in germinal centers.

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The role of CD40 in the regulation of humoral and cell-mediated immunity

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B70 antigen is a second ligand for CTLA-4 and CD28.

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7 January 2021

CD40 ligand and its role in X-linked hyper-IgM syndrome

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7 January 2021

Impairment of antigen-specific T-cell priming in mice lacking CD40 ligand

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CD40 ligand-transduced co-stimulation of T cells in the development of helper function

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7 January 2021

In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. II. Prolonged suppression of the humoral immune response by an antibody to the ligand for CD40, gp39.

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7 January 2021

In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. I. In vivo expression of CD40 ligand, cytokines, and antibody production delineates sites of cognate T-B cell interactions

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gp39-CD40 interactions are essential for germinal center formation and the development of B cell memory

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7 January 2021

Blocking the CD40L-CD40 interaction in vivo specifically prevents the priming of T helper 1 cells through the inhibition of interleukin 12 secretion

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7 January 2021

CD40-CD40 ligand interactions in experimental allergic encephalomyelitis and multiple sclerosis

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7 January 2021

Prevention of collagen-induced arthritis with an antibody to gp39, the ligand for CD40

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7 January 2021

The relative contribution of the CD28 and gp39 costimulatory pathways in the clonal expansion and pathogenic acquisition of self-reactive T cells

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CD40 on human endothelial cells: inducibility by cytokines and functional regulation of adhesion molecule expression.

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Expression of functional CD40 by vascular endothelial cells

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7 January 2021

Functional interactions of T cells with endothelial cells: the role of CD40L-CD40-mediated signals

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7 January 2021

Blockade of CD40-CD154 interferes with human T cell engraftment in scid mice

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7 January 2021

Rapid PCR-cloning of full-length mouse immunoglobulin variable regions

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7 January 2021

Replacing the complementarity-determining regions in a human antibody with those from a mouse

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7 January 2021

Reshaping human antibodies: grafting an antilysozyme activity.

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7 January 2021

Anatomy of the antibody molecule

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7 January 2021

Effect of gamma rays at the dihydrofolate reductase locus: deletions and inversions.

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7 January 2021

Human monoclonal antibodies isolated from spontaneous Epstein-Barr virus-transformed tumors of Hu-SPL-SCID mice and specific for fusion protein display broad neutralizing activity toward respiratory syncytial virus

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7 January 2021

A directory of human germ-line V kappa segments reveals a strong bias in their usage

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7 January 2021

A map of the human immunoglobulin VH locus completed by analysis of the telomeric region of chromosome 14q.

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7 January 2021

Mice deficient for the CD40 ligand

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7 January 2021

The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome

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7 January 2021

10.1016/S1567-5769(00)00020-5

Identifiers

DOI

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8 May 2018

PubMed ID

11360929

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8 May 2018