Role of receptor kinase in long-term desensitization of the cardiac muscarinic receptor-K+ channel system. (Q52861366)

9 May 2018

title

Role of receptor kinase in long-term desensitization of the cardiac muscarinic receptor-K+ channel system. (English)

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9 May 2018

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Z Shui

1

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9 May 2018

I A Khan

2

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H Tsuga

3

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H Dobrzynski

4

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T Haga

5

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Z Henderson

6

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M R Boyett

7

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publication date

1 August 2002

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9 May 2018

American Journal of Physiology Heart and Circulatory Physiology

published in

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9 May 2018

volume

283

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issue

2

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9 May 2018

page(s)

H819-28

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9 May 2018

Agonist-dependent desensitization of the kappa opioid receptor by G protein receptor kinase and beta-arrestin

cites work

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https://api.crossref.org/works/10.1152%2FAJPHEART.00515.2001

Overexpression of monomeric and multimeric GIRK4 subunits in rat atrial myocytes removes fast desensitization and reduces inward rectification of muscarinic K(+) current (I(K(ACh))). Evidence for functional homomeric GIRK4 channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00515.2001

The fade of the response to acetylcholine at the rabbit isolated sino-atrial node

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00515.2001

In vivo downregulation of M2 receptors revealed by measurement of muscarinic K+ current in cultured guinea-pig atrial myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00515.2001

Evidence that the nucleotide exchange and hydrolysis cycle of G proteins causes acute desensitization of G-protein gated inward rectifier K+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00515.2001

Desensitization to acetylcholine in single sinoatrial node cells isolated from rabbit hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00515.2001

Activation of a GTP-binding protein and a GTP-binding-protein-coupled receptor kinase (beta-adrenergic-receptor kinase-1) by a muscarinic receptor m2 mutant lacking phosphorylation sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00515.2001

Mechanism of rapid desensitization of muscarinic K+ current in adult rat and guinea pig atrial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00515.2001

Receptor-mediated hydrolysis of plasma membrane messenger PIP2 leads to K+-current desensitization

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00515.2001

Short-term desensitization of muscarinic K+ channel current in isolated atrial myocytes and possible role of GTP-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00515.2001

Secondary AV conduction responses during tonic vagal stimulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00515.2001

Depletion of phosphatidylinositol 4,5-bisphosphate by activation of phospholipase C-coupled receptors causes slow inhibition but not desensitization of G protein-gated inward rectifier K+ current in atrial myocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00515.2001

Location of agonist-dependent-phosphorylation sites in the third intracellular loop of muscarinic acetylcholine receptors (m2 subtype).

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00515.2001

Ionic basis of depressed automaticity and conduction by acetylcholine in rabbit AV node

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00515.2001

Two homologous phosphorylation domains differentially contribute to desensitization and internalization of the m2 muscarinic acetylcholine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00515.2001

Activation of the cloned muscarinic potassium channel by G protein beta gamma subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00515.2001

ATP-dependent desensitization of the muscarinic K+ channel in rat atrial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00515.2001

Receptor kinase-dependent desensitization of the muscarinic K+ current in rat atrial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00515.2001

Control of the cardiac muscarinic K+ channel by beta-arrestin 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00515.2001

Evidence of involvement of GIRK1/GIRK4 in long-term desensitization of cardiac muscarinic K+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00515.2001

Regional differences in the negative inotropic effect of acetylcholine within the canine ventricle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00515.2001

10.1152/AJPHEART.00515.2001

21 January 2018

Identifiers

DOI

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9 May 2018

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9 May 2018