SIK inhibition in human myeloid cells modulates TLR and IL-1R signaling and induces an anti-inflammatory phenotype. (Q52901372)

9 May 2018

title

SIK inhibition in human myeloid cells modulates TLR and IL-1R signaling and induces an anti-inflammatory phenotype. (English)

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9 May 2018

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ChEBI release 2020-05-28

4

Cem Gabay

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9 May 2018

author name string

Maria Stella Lombardi

series ordinal

1

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9 May 2018

Corine Gilliéron

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2

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9 May 2018

Damien Dietrich

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3

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9 May 2018

publication date

20 November 2015

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Journal of Leukocyte Biology

published in

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9 May 2018

volume

99

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9 May 2018

issue

5

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9 May 2018

page(s)

711-721

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9 May 2018

Alternatively activated macrophages elicited by helminth infection can be reprogrammed to enable microbial killing

cites work

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

Interferon-gamma reverses the immunosuppressive and protumoral properties and prevents the generation of human tumor-associated macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

Macrophage plasticity and polarization: in vivo veritas

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

The M1 and M2 paradigm of macrophage activation: time for reassessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

Transcriptome-based network analysis reveals a spectrum model of human macrophage activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

Resolution of inflammation: the beginning programs the end

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

Chronic inflammation: a failure of resolution?

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

Regulatory macrophages: setting the threshold for therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

Altered M1/M2 activation patterns of monocytes in severe relapsing experimental rat model of multiple sclerosis. Amelioration of clinical status by M2 activated monocyte administration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

Reversing lipopolysaccharide toxicity by ligating the macrophage Fc gamma receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

Interleukin-10 therapy--review of a new approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

Strategies for use of IL-10 or its antagonists in human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

Phosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated and regulatory macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

The clinically approved drugs dasatinib and bosutinib induce anti-inflammatory macrophages by inhibiting the salt-inducible kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

Salt-inducible kinase (SIK) isoforms: their involvement in steroidogenesis and adipogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

Protein kinase networks that limit TLR signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

The TLR and IL-1 signalling network at a glance

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

Small-molecule screening identifies inhibition of salt-inducible kinases as a therapeutic strategy to enhance immunoregulatory functions of dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

IL-1 pathways in inflammation and human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

Interleukin-1 in the pathogenesis and treatment of inflammatory diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

Differential regulation of chemokine production by Fcgamma receptor engagement in human monocytes: association of CCL1 with a distinct form of M2 monocyte activation (M2b, Type 2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

Polarization profiles of human M-CSF-generated macrophages and comparison of M1-markers in classically activated macrophages from GM-CSF and M-CSF origin

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

A new mathematical model for relative quantification in real-time RT-PCR

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

Systematic validation of specific phenotypic markers for in vitro polarized human macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

Exploring the full spectrum of macrophage activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

Biochemical and functional characterization of three activated macrophage populations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

The chemokine system in diverse forms of macrophage activation and polarization

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

Leptin-mediated increases in catecholamine signaling reduce adipose tissue inflammation via activation of macrophage HDAC4

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

PGE(2) induces macrophage IL-10 production and a regulatory-like phenotype via a protein kinase A-SIK-CRTC3 pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

LKB1-dependent signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

Activation of protein kinase C zeta by peroxynitrite regulates LKB1-dependent AMP-activated protein kinase in cultured endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

AMPKα1 deficiency amplifies proinflammatory myeloid APC activity and CD40 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

The regulation of IL-10 production by immune cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

Identification of a macrophage-specific chromatin signature in the IL-10 locus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

Salt-inducible kinases 1 and 3 negatively regulate Toll-like receptor 4-mediated signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

Salt-inducible kinase 3 deficiency exacerbates lipopolysaccharide-induced endotoxin shock accompanied by increased levels of pro-inflammatory molecules in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

Methotrexate--how does it really work?

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1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

Apremilast is a selective PDE4 inhibitor with regulatory effects on innate immunity

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1 reference

https://api.crossref.org/works/10.1189%2FJLB.2A0715-307R

21 January 2018

Identifiers

DOI

10.1189/JLB.2A0715-307R

1 reference

9 May 2018

1 reference

9 May 2018