Allo-specific T-cells encoding for viral IL-10 exert strong immunomodulatory effects in vitro but fail to prevent graft rejection. (Q52940814)

9 May 2018

title

Allo-specific T-cells encoding for viral IL-10 exert strong immunomodulatory effects in vitro but fail to prevent graft rejection. (English)

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9 May 2018

author

Birgit Sawitzki

7

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Thomas Ritter

10

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Hans-Dieter Volk

9

object named as

Hans-Dieter Volk

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9 May 2018

author name string

Christine Brandt

1

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9 May 2018

Jun Yang

2

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Isabella Schmitt-Knosalla

3

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9 May 2018

Anja Siepert

4

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Markus H Hammer

5

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Katrin Vogt

6

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Manfred Lehmann

8

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language of work or name

English

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publication date

1 February 2005

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9 May 2018

American Journal of Transplantation

published in

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volume

5

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issue

2

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page(s)

268-281

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9 May 2018

Regulatory T cells in transplantation tolerance

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1 reference

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Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression

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Interleukin 10 (IL-10) inhibits the release of proinflammatory cytokines from human polymorphonuclear leukocytes. Evidence for an autocrine role of tumor necrosis factor and IL-1 beta in mediating the production of IL-8 triggered by lipopolysacchari

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Regulatory cells potentiate the efficacy of IL-4 gene transfer by up-regulating Th2-dependent expression of protective molecules in the infectious tolerance pathway in transplant recipients

21 January 2018

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Potential of allospecific gene-engineered T cells in transplantation gene therapy: specific T cell activation determines transgene expression in vitro and in vivo

21 January 2018

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CD4 T-helper cells engineered to produce IL-10 prevent allergen-induced airway hyperreactivity and inflammation

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Feline Immunodeficiency Virus-Mediated Viral Interleukin-10 Gene Transfer Prolongs Non-Vascularized Cardiac Allograft Survival

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21 January 2018

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Bag-1 up-regulation in anti-CD4 mAb treated allo-activated T cells confers resistance to apoptosis

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21 January 2018

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Viral IL-10 gene transfer inhibits the expression of multiple chemokine and chemokine receptor genes induced by inflammatory or adaptive immune stimuli

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Regulatory T cells overexpress a subset of Th2 gene transcripts

21 January 2018

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10.1111/J.1600-6143.2005.00689.X

21 January 2018

Identifiers

DOI

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9 May 2018

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9 May 2018