Plexin-B1 signalling promotes androgen receptor translocation to the nucleus. (Q52942729)

9 May 2018

title

Plexin-B1 signalling promotes androgen receptor translocation to the nucleus. (English)

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9 May 2018

author name string

M Williamson

series ordinal

1

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9 May 2018

P de Winter

series ordinal

2

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9 May 2018

J R Masters

series ordinal

3

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9 May 2018

language of work or name

English

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publication date

18 May 2015

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9 May 2018

published in

Oncogene

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9 May 2018

volume

35

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9 May 2018

issue

8

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9 May 2018

page(s)

1066-1072

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9 May 2018

Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates

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The semaphorin receptor plexin-B1 specifically interacts with active Rac in a ligand-dependent manner

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Direct interaction of Rnd1 with Plexin-B1 regulates PDZ-RhoGEF-mediated Rho activation by Plexin-B1 and induces cell contraction in COS-7 cells

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Binding of Rac1, Rnd1, and RhoD to a Novel Rho GTPase Interaction Motif Destabilizes Dimerization of the Plexin-B1 Effector Domain

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Androgen receptor serine 81 phosphorylation mediates chromatin binding and transcriptional activation.

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Subcellular localization modulates activation function 1 domain phosphorylation in the androgen receptor

21 January 2018

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CDK9 regulates AR promoter selectivity and cell growth through serine 81 phosphorylation

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B-plexins control microtubule dynamics and dendrite morphology of hippocampal neurons.

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Sema4D/plexin-B1 activates GSK-3beta through R-Ras GAP activity, inducing growth cone collapse

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RanBPM contributes to Semaphorin3A signaling through plexin-A receptors

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Plexins Are GTPase-Activating Proteins for Rap and Are Activated by Induced Dimerization

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Loss of Plexin B1 is highly prognostic in low proliferating ER positive breast cancers--results of a large scale microarray analysis

31 March 2020

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IGF binding protein-5 synthesis is regulated by testosterone through transcriptional mechanisms in androgen responsive cells

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2015.160

Androgen receptor up-regulates insulin-like growth factor binding protein-5 (IGFBP-5) expression in a human prostate cancer xenograft

31 March 2020

1 reference

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Long-term presence of androgens and anti-androgens modulate EGF-receptor expression and MAP-kinase phosphorylation in androgen receptor-prostate positive cancer cells

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25982277

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Overexpressed androgen receptor linked to p21WAF1 silencing may be responsible for androgen independence and resistance to apoptosis of a prostate cancer cell line.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25982277

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2015.160

1 reference

9 May 2018

1 reference

9 May 2018