The receptor CD44 is associated with systemic insulin resistance and proinflammatory macrophages in human adipose tissue. (Q52945138)

9 May 2018

title

The receptor CD44 is associated with systemic insulin resistance and proinflammatory macrophages in human adipose tissue. (English)

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9 May 2018

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7

Atul J Butte

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9 May 2018

Li Fen Liu

1

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9 May 2018

Keiichi Kodama

2

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9 May 2018

Ke Wei

3

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9 May 2018

Lorna L Tolentino

4

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9 May 2018

Okmi Choi

5

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9 May 2018

Edgar G Engleman

6

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9 May 2018

Tracey McLaughlin

8

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9 May 2018

publication date

9 May 2015

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9 May 2018

published in

Diabetologia

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9 May 2018

volume

58

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9 May 2018

page(s)

1579-1586

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9 May 2018

issue

7

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9 May 2018

https://scigraph.springernature.com/pub.10.1007/s00125-015-3603-y

exact match

0 references

cites work

Obesity is associated with macrophage accumulation in adipose tissue

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Pro-inflammatory CD11c+CD206+ adipose tissue macrophages are associated with insulin resistance in human obesity

21 January 2018

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Expression-based genome-wide association study links the receptor CD44 in adipose tissue with type 2 diabetes

21 January 2018

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Osteopontin expression in human and murine obesity: extensive local up-regulation in adipose tissue but minimal systemic alterations.

21 January 2018

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Osteopontin is an activator of human adipose tissue macrophages and directly affects adipocyte function.

21 January 2018

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Anti-CD44 antibody treatment lowers hyperglycemia and improves insulin resistance, adipose inflammation, and hepatic steatosis in diet-induced obese mice

21 January 2018

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Elevated expression of osteopontin may be related to adipose tissue macrophage accumulation and liver steatosis in morbid obesity

21 January 2018

1 reference

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Osteopontin mediates obesity-induced adipose tissue macrophage infiltration and insulin resistance in mice

21 January 2018

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

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CD44 plays a critical role in regulating diet-induced adipose inflammation, hepatic steatosis, and insulin resistance

21 January 2018

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CCR2 and CD44 promote inflammatory cell recruitment during fatty liver formation in a lithogenic diet fed mouse model

21 January 2018

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The adhesion receptor CD44 promotes atherosclerosis by mediating inflammatory cell recruitment and vascular cell activation

21 January 2018

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Osteopontin: a novel inflammatory mediator of cardiovascular disease

21 January 2018

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Hyaluronan (HA) fragments induce chemokine gene expression in alveolar macrophages. The role of HA size and CD44.

21 January 2018

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Osteopontin modulates CD44‐dependent chemotaxis of peritoneal macrophages through G‐protein‐coupled receptors: Evidence of a role for an intracellular form of osteopontin

21 January 2018

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Receptor-ligand interaction between CD44 and osteopontin (Eta-1)

21 January 2018

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Neutralization of osteopontin inhibits obesity-induced inflammation and insulin resistance.

21 January 2018

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MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity

21 January 2018

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Plasma Osteopontin Levels and Expression in Adipose Tissue Are Increased in Obesity

21 January 2018

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Enhanced proportion of small adipose cells in insulin-resistant vs insulin-sensitive obese individuals implicates impaired adipogenesis

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12 December 2020

Assessment of insulin resistance with the insulin suppression test and the euglycemic clamp

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12 December 2020

Requirement for CD44 in activated T cell extravasation into an inflammatory site

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12 December 2020

Evaluation of octreotide to assess insulin-mediated glucose disposal by the insulin suppression test

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12 December 2020

CD44 contributes to T cell activation

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12 December 2020

Evidence for a role of osteopontin in macrophage infiltration in response to pathological stimuli in vivo

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METABOLISM OF ISOLATED FAT CELLS. I. EFFECTS OF HORMONES ON GLUCOSE METABOLISM AND LIPOLYSIS

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12 December 2020

10.1007/S00125-015-3603-Y

Identifiers

DOI

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9 May 2018

PubMed ID

25952479

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9 May 2018