Liver inflammation abrogates immunological tolerance induced by Kupffer cells. (Q52956130)

9 May 2018

title

Liver inflammation abrogates immunological tolerance induced by Kupffer cells. (English)

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Nico van Rooijen

8

object named as

Nico van Rooijen

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Florent Ginhoux

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Gwendalyn J. Randolph

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object named as

Gwendalyn J Randolph

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Frank Tacke

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object named as

Frank Tacke

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author name string

Felix Heymann

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Julia Peusquens

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Isis Ludwig-Portugall

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Marlene Kohlhepp

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Can Ergen

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Patricia Niemietz

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Christian Martin

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Tom Luedde

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Christian Kurts

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Christian Trautwein

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language of work or name

English

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publication date

22 April 2015

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published in

Hepatology

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volume

62

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issue

1

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page(s)

279-291

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Regulatory T cells: mechanisms of differentiation and function

cites work

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Disease tolerance as a defense strategy

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Hepatic T cells and liver tolerance

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Hepatic allograft-derived Kupffer cells regulate T cell response in rats

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Immune tolerance: what is unique about the liver

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Pathogenesis of chronic viral hepatitis: differential roles of T cells and NK cells

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Dynamic Regulation of CD8 T Cell Tolerance Induction by Liver Sinusoidal Endothelial Cells

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Differential migration of passenger leukocytes and rapid deletion of naive alloreactive CD8 T cells after mouse liver transplantation

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Hepatic regulatory T cells and Kupffer cells are crucial mediators of systemic T cell tolerance to antigens targeting murine liver.

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Priming of CD4+ T cells by liver sinusoidal endothelial cells induces CD25low forkhead box protein 3- regulatory T cells suppressing autoimmune hepatitis

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Defective thymopoiesis and poor peripheral homeostatic replenishment of T-helper cells cause T-cell lymphopenia in cirrhosis

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Immature monocytes acquire antigens from other cells in the bone marrow and present them to T cells after maturing in the periphery

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Chemokine receptor CXCR6-dependent hepatic NK T Cell accumulation promotes inflammation and liver fibrosis

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Hepatic macrophage migration and differentiation critical for liver fibrosis is mediated by the chemokine receptor C-C motif chemokine receptor 8 in mice.

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Pharmacological inhibition of the chemokine CCL2 (MCP-1) diminishes liver macrophage infiltration and steatohepatitis in chronic hepatic injury

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Kidney dendritic cell activation is required for progression of renal disease in a mouse model of glomerular injury

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Liver antigen-presenting cells

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A lineage of myeloid cells independent of Myb and hematopoietic stem cells

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Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis

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Macrophage heterogeneity in liver injury and fibrosis

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Hepatic recruitment of the inflammatory Gr1+monocyte subset upon liver injury promotes hepatic fibrosis

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Immune tolerance in liver disease

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Induction of tolerance in CD8+ T cells to a transgenic autoantigen expressed in the liver does not require cross-presentation

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Immune surveillance by the liver

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Mechanism of T cell tolerance induction by murine hepatic Kupffer cells

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IL-10, regulatory T cells, and Kupffer cells mediate tolerance in concanavalin A-induced liver injury in mice.

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7 January 2021

IL-10 down-regulates T cell activation by antigen-presenting liver sinusoidal endothelial cells through decreased antigen uptake via the mannose receptor and lowered surface expression of accessory molecules

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Galactosylated LDL nanoparticles: a novel targeting delivery system to deliver antigen to macrophages and enhance antigen specific T cell responses

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Peptide-Functionalized Gold Nanorods Increase Liver Injury in Hepatitis

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Targeting dexamethasone to Kupffer cells: Effects on liver inflammation and fibrosis in rats

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Monocyte recruitment during infection and inflammation

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Liver-resident macrophage necroptosis orchestrates type 1 microbicidal inflammation and type-2-mediated tissue repair during bacterial infection

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Monocyte subsets in human liver disease show distinct phenotypic and functional characteristics

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Bacterial infections in cirrhosis: a position statement based on the EASL Special Conference 2013.

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Identifiers

DOI

10.1002/HEP.27793

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9 May 2018

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