Common sequence variations in the P2Y12 and CYP3A5 genes do not explain the variability in the inhibitory effects of clopidogrel therapy. (Q53005242)

10 May 2018

title

Common sequence variations in the P2Y12 and CYP3A5 genes do not explain the variability in the inhibitory effects of clopidogrel therapy. (English)

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10 May 2018

1 reference

5

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Robert F. Storey

8

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Pascale Gaussem

6

object named as

Pascale Gaussem

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Simon M G Smith

1

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Heather M Judge

2

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Gary Peters

3

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Martin Armstrong

4

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Martina E Daly

7

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publication date

1 June 2006

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10 May 2018

published in

Platelets

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volume

17

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issue

4

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10 May 2018

page(s)

250-258

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10 May 2018

Double-blind study of the safety of clopidogrel with and without a loading dose in combination with aspirin compared with ticlopidine in combination with aspirin after coronary stenting : the clopidogrel aspirin stent international cooperative study

cites work

1 reference

https://api.crossref.org/works/10.1080%2F09537100500475844

A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). CAPRIE Steering Committee

21 January 2018

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Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation

21 January 2018

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Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevation

21 January 2018

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Identification of low responders to a 300-mg clopidogrel loading dose in patients undergoing coronary stenting.

21 January 2018

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High clopidogrel loading dose during coronary stenting: effects on drug response and interindividual variability.

21 January 2018

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Clopidogrel for coronary stenting: response variability, drug resistance, and the effect of pretreatment platelet reactivity

21 January 2018

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Variability in platelet responsiveness to clopidogrel among 544 individuals.

21 January 2018

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Resistance to thienopyridines: clinical detection of coronary stent thrombosis by monitoring of vasodilator-stimulated phosphoprotein phosphorylation

21 January 2018

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https://api.crossref.org/works/10.1080%2F09537100500475844

Clopidogrel resistance is associated with increased risk of recurrent atherothrombotic events in patients with acute myocardial infarction

21 January 2018

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P2y(12), a new platelet ADP receptor, target of clopidogrel

21 January 2018

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The metabolism of clopidogrel is catalyzed by human cytochrome P450 3A and is inhibited by atorvastatin

21 January 2018

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https://api.crossref.org/works/10.1080%2F09537100500475844

Genetic contribution to variable human CYP3A-mediated metabolism

21 January 2018

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Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

21 January 2018

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Adenosine diphosphate-induced platelet aggregation is associated with P2Y12 gene sequence variations in healthy subjects.

21 January 2018

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P2Y12 H2 haplotype is associated with peripheral arterial disease: a case-control study.

21 January 2018

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Randomized trial of high loading dose of clopidogrel for reduction of periprocedural myocardial infarction in patients undergoing coronary intervention: results from the ARMYDA-2 (Antiplatelet therapy for Reduction of MYocardial Damage during Angiop

21 January 2018

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P2Y12 gene H2 haplotype is not associated with increased adenosine diphosphate-induced platelet aggregation after initiation of clopidogrel therapy with a high loading dose

21 January 2018

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Lack of association between the P2Y12 receptor gene polymorphism and platelet response to clopidogrel in patients with coronary artery disease

21 January 2018

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Effect of a high loading dose of clopidogrel on platelet function in patients undergoing coronary stent placement

21 January 2018

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The relation of dosing to clopidogrel responsiveness and the incidence of high post-treatment platelet aggregation in patients undergoing coronary stenting

21 January 2018

1 reference

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10.1080/09537100500475844

21 January 2018

Identifiers

DOI

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10 May 2018

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10 May 2018