Glyoxalase-1 overexpression reduces endothelial dysfunction and attenuates early renal impairment in a rat model of diabetes. (Q53085119)

11 May 2018

title

Glyoxalase-1 overexpression reduces endothelial dysfunction and attenuates early renal impairment in a rat model of diabetes. (English)

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11 May 2018

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11

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Allan Flyvbjerg

5

Allan Flyvbjerg

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Jonas Sieber

7

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Jakob A Østergaard

Jakob A Østergaard

Coenraad Dirk Adriaan Stehouwer

4

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12

Coen D A Stehouwer

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11 May 2018

Casper G. Schalkwijk

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Casper G Schalkwijk

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11 May 2018

author name string

Olaf Brouwers

1

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11 May 2018

Petra M G Niessen

2

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11 May 2018

Toshio Miyata

3

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11 May 2018

Carine J Peutz-Kootstra

6

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11 May 2018

Peter H Mundel

8

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11 May 2018

Michael Brownlee

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Ben J A Janssen

10

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publication date

26 October 2013

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11 May 2018

published in

Diabetologia

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11 May 2018

volume

57

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11 May 2018

page(s)

224-235

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11 May 2018

issue

1

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11 May 2018

https://scigraph.springernature.com/pub.10.1007/s00125-013-3088-5

exact match

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cites work

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Overexpression of glyoxalase-I in bovine endothelial cells inhibits intracellular advanced glycation endproduct formation and prevents hyperglycemia-induced increases in macromolecular endocytosis

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Glycation of mitochondrial proteins from diabetic rat kidney is associated with excess superoxide formation

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Susceptibility to diabetic nephropathy is related to dicarbonyl and oxidative stress

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Methylglyoxal is a predictor in type 2 diabetic patients of intima-media thickening and elevation of blood pressure

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Plasma levels of advanced glycation endproducts Nε-(carboxymethyl)lysine, Nε-(carboxyethyl)lysine, and pentosidine are not independently associated with cardiovascular disease in individuals with or without type 2 diabetes: the Hoorn and CODAM studi

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Methylglyoxal and methylglyoxal-arginine adducts do not directly inhibit endothelial nitric oxide synthase

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Role of adhesion molecules in vascular regulation and damage

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Higher plasma levels of advanced glycation end products are associated with incident cardiovascular disease and all-cause mortality in type 1 diabetes: a 12-year follow-up study

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Aminoguanidine prevents arterial stiffening and cardiac hypertrophy in streptozotocin-induced diabetes in rats.

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Interaction of metabolic and haemodynamic factors in mediating experimental diabetic nephropathy

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The impaired renal vasodilator response attributed to endothelium-derived hyperpolarizing factor in streptozotocin--induced diabetic rats is restored by 5-methyltetrahydrofolate.

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Candesartan attenuates diabetic retinal vascular pathology by restoring glyoxalase-I function

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Effects of aminoguanidine in preventing experimental diabetic nephropathy are related to the duration of treatment

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12 December 2020

Development of glomerular lesions in experimental long-term diabetes in the rat

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12 December 2020

Overexpression of glyoxalase-I reduces hyperglycemia-induced levels of advanced glycation end products and oxidative stress in diabetic rats

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12 December 2020

Advanced glycation endproducts promote adhesion molecule (VCAM-1, ICAM-1) expression and atheroma formation in normal rabbits

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12 December 2020

The breakdown of preexisting advanced glycation end products is associated with reduced renal fibrosis in experimental diabetes.

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12 December 2020

Protection against methylglyoxal-derived AGEs by regulation of glyoxalase 1 prevents retinal neuroglial and vasodegenerative pathology

1 reference

12 December 2020

Increased accumulation of the glycoxidation product Nepsilon-(carboxymethyl)lysine in hearts of diabetic patients: generation and characterisation of a monoclonal anti-CML antibody

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12 December 2020

Markers of Endothelial Dysfunction and Inflammation in Type 1 Diabetic Patients With or Without Diabetic Nephropathy Followed for 10 Years: Association with mortality and decline of glomerular filtration rate

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12 December 2020

A novel inhibitor of advanced glycation end-product formation inhibits mesenteric vascular hypertrophy in experimental diabetes

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12 December 2020

Quantification of glyoxal, methylglyoxal and 3-deoxyglucosone in blood and plasma by ultra performance liquid chromatography tandem mass spectrometry: evaluation of blood specimen

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12 December 2020

Endothelial cells in physiology and in the pathophysiology of vascular disorders

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12 December 2020

Quantitative UPLC-MS/MS analysis of underivatised amino acids in body fluids is a reliable tool for the diagnosis and follow-up of patients with inborn errors of metabolism

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12 December 2020

The assay of S-D-lactoylglutathione in biological systems

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12 December 2020

N-acetylcysteine prevents nitrosative stress-associated depression of blood pressure and heart rate in streptozotocin diabetic rats

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12 December 2020

Diabetes-induced endothelial dysfunction in streptozotocin-treated rats: role of prostaglandin endoperoxides and free radicals

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12 December 2020

Intensive Glycemic Control and the Prevention of Cardiovascular Events: Implications of the ACCORD, ADVANCE, and VA Diabetes Trials

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12 December 2020

10.1007/S00125-013-3088-5

Identifiers

DOI

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11 May 2018

PubMed ID

24162587

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11 May 2018