TRAF6 mediates ubiquitination of KIF23/MKLP1 and is required for midbody ring degradation by selective autophagy. (Q53086467)

11 May 2018

title

TRAF6 mediates ubiquitination of KIF23/MKLP1 and is required for midbody ring degradation by selective autophagy. (English)

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11 May 2018

main subject

protein ubiquitination

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6

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Harald Stenmark

5

object named as

Harald Stenmark

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11 May 2018

Pauline Isakson

1

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11 May 2018

Alf Håkon Lystad

2

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11 May 2018

Kamilla Breen

3

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Gerbrand Koster

4

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11 May 2018

publication date

1 December 2013

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11 May 2018

published in

Autophagy

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11 May 2018

volume

9

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issue

12

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11 May 2018

page(s)

1955-1964

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Autophagy: renovation of cells and tissues

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p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

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A role for NBR1 in autophagosomal degradation of ubiquitinated substrates

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p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

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Structural basis for sorting mechanism of p62 in selective autophagy

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p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy

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The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy

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Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes

21 January 2018

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Midbody ring disposal by autophagy is a post-abscission event of cytokinesis

21 January 2018

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Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity

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Midbody and primary cilium of neural progenitors release extracellular membrane particles enriched in the stem cell marker prominin-1

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Dynamic regulation of ubiquitylation and deubiquitylation at the central spindle during cytokinesis

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Final stages of cytokinesis and midbody ring formation are controlled by BRUCE

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Mechanism of Aurora-B degradation and its dependency on intact KEN and A-boxes: identification of an aneuploidy-promoting property

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A Cul3-based E3 ligase removes Aurora B from mitotic chromosomes, regulating mitotic progression and completion of cytokinesis in human cells

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Chromosome alignment and segregation regulated by ubiquitination of survivin

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Central spindle assembly and cytokinesis require a kinesin-like protein/RhoGAP complex with microtubule bundling activity

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TRAF6-mediated ubiquitination regulates nuclear translocation of NRIF, the p75 receptor interactor

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TRAF6 and A20 regulate lysine 63-linked ubiquitination of Beclin-1 to control TLR4-induced autophagy

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A role for ubiquitin in selective autophagy

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Interactions with LC3 and polyubiquitin chains link nbr1 to autophagic protein turnover

21 January 2018

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Structural basis for Arf6-MKLP1 complex formation on the Flemming body responsible for cytokinesis.

21 January 2018

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Proliferating versus differentiating stem and cancer cells exhibit distinct midbody-release behaviour.

21 January 2018

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Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domain

21 January 2018

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Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference

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21 January 2018

Identifiers

DOI

10.4161/AUTO.26085

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11 May 2018

PubMed ID

24128730

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11 May 2018