Comprehensive analysis of mitochondrial permeability transition pore activity in living cells using fluorescence-imaging-based techniques. (Q53097951)

11 May 2018

title

Comprehensive analysis of mitochondrial permeability transition pore activity in living cells using fluorescence-imaging-based techniques. (English)

1 reference

11 May 2018

author

Mariusz R Wieckowski

5

1 reference

11 May 2018

Paolo Pinton

6

1 reference

11 May 2018

Massimo Bonora

1

Massimo Bonora

1 reference

11 May 2018

Carlotta Giorgi

4

Carlotta Giorgi

1 reference

11 May 2018

Claudia Morganti

2

Claudia Morganti

1 reference

11 May 2018

Giampaolo Morciano

3

Giampaolo Morciano

1 reference

11 May 2018

publication date

12 May 2016

1 reference

11 May 2018

published in

Nature Protocols

1 reference

11 May 2018

volume

11

1 reference

11 May 2018

page(s)

1067-1080

1 reference

11 May 2018

issue

6

1 reference

11 May 2018

https://scigraph.springernature.com/pub.10.1038/nprot.2016.064

exact match

0 references

cites work

The mitochondrial permeability transition.

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Physiological and pathological roles of the mitochondrial permeability transition pore in the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

The mitochondrial permeability transition pore: molecular nature and role as a target in cardioprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

The C Ring of the F1Fo ATP Synthase Forms the Mitochondrial Permeability Transition Pore: A Critical Appraisal

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

The mitochondrial permeability transition: a current perspective on its identity and role in ischaemia/reperfusion injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Molecular identity of the mitochondrial permeability transition pore and its role in ischemia-reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Role of the c subunit of the FO ATP synthase in mitochondrial permeability transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

The mitochondrial permeability transition pore is a dispensable element for mitochondrial calcium efflux

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

An uncoupling channel within the c-subunit ring of the F1FO ATP synthase is the mitochondrial permeability transition pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Potential role of subunit c of F0F1-ATPase and subunit c of storage body in the mitochondrial permeability transition. Effect of the phosphorylation status of subunit c on pore opening

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

CALCIUM ION ACCUMULATION AND VOLUME CHANGES OF ISOLATED LIVER MITOCHONDRIA. REVERSAL OF CALCIUM ION-INDUCED SWELLING

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

CALCIUM ION ACCUMULATION AND VOLUME CHANGES OF ISOLATED LIVER MITOCHONDRIA. CALCIUM ION-INDUCED SWELLING

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Inhibiting mitochondrial permeability transition pore opening at reperfusion protects against ischaemia-reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Fatty acid-induced uncoupling of oxidative phosphorylation is partly due to opening of the mitochondrial permeability transition pore.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Regulation of mitochondrial permeability transition pore by PINK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

The mitochondrial permeability transition pore and its role in cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Mitochondrial permeability transition pore and calcium handling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

The roles of phosphate and the phosphate carrier in the mitochondrial permeability transition pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

A novel apoptosis-like pathway, independent of mitochondria and caspases, induced by curcumin in human lymphoblastoid T (Jurkat) cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Mitochondrial non-specific pores remain closed during cardiac ischaemia, but open upon reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Mitochondrial permeability transition can be directly monitored in living neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Transient mitochondrial permeability transition pore opening mediates preconditioning-induced protection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Transient and long-lasting openings of the mitochondrial permeability transition pore can be monitored directly in intact cells by changes in mitochondrial calcein fluorescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Opening of the mitochondrial permeability transition pore causes matrix expansion and outer membrane rupture in Fas-mediated hepatic apoptosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Regulation of mitochondrial matrix volume

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Assessing mitochondrial morphology and dynamics using fluorescence wide-field microscopy and 3D image processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Quantitative analysis of mitochondrial morphology and membrane potential in living cells using high-content imaging, machine learning, and morphological binning

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Multi-parametric analysis and modeling of relationships between mitochondrial morphology and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Simultaneous monitoring of ionophore- and inhibitor-mediated plasma and mitochondrial membrane potential changes in cultured neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Physiological cytosolic Ca2+ transients evoke concurrent mitochondrial depolarizations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Oxidative damage to mitochondria is mediated by the Ca(2+)-dependent inner-membrane permeability transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Mitochondrial permeability transition and oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Opening of the mitochondrial permeability transition pore by uncoupling or inorganic phosphate in the presence of Ca2+ is dependent on mitochondrial-generated reactive oxygen species.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Long-chain fatty acids promote opening of the reconstituted mitochondrial permeability transition pore.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Complexes between kinases, mitochondrial porin and adenylate translocator in rat brain resemble the permeability transition pore.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

The mitochondrial permeability transition pore (PTP) - an example of multiple molecular exaptation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Chimeric green fluorescent protein as a tool for visualizing subcellular organelles in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Fiji: an open-source platform for biological-image analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Mitochondrial membrane permeabilization in cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Structure-guided evolution of cyan fluorescent proteins towards a quantum yield of 93%.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Red emissive two-photon probe for real-time imaging of mitochondria trafficking.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Far-red fluorescent protein excitable with red lasers for flow cytometry and superresolution STED nanoscopy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Effect of transient and permanent permeability transition pore opening on NAD(P)H localization in intact cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Endoplasmic reticulum stress induces calcium-dependent permeability transition, mitochondrial outer membrane permeabilization and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Menadione triggers cell death through ROS-dependent mechanisms involving PARP activation without requiring apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Changes in mitochondrial dynamics during ceramide-induced cardiomyocyte early apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Mitochondrial membrane potential probes and the proton gradient: a practical usage guide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

JC-1, but not DiOC6(3) or rhodamine 123, is a reliable fluorescent probe to assess delta psi changes in intact cells: implications for studies on mitochondrial functionality during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

The Ca2+-induced membrane transition in mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Multi-parameter measurement of the permeability transition pore opening in isolated mouse heart mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

The mitochondrial membrane permeability transition induced by inorganic phosphate or inorganic arsenate. A comparative study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

The peptide mastoparan is a potent facilitator of the mitochondrial permeability transition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

Peripheral benzodiazepine receptor ligand, PK11195 induces mitochondria cytochrome c release and dissipation of mitochondria potential via induction of mitochondria permeability transition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.064

[Treatment of pulmonary infections probably caused by fungi in patients with acute leukemia with chlotrimazole (author's transl)]

31 March 2020

1 reference

12 December 2020

The voltage sensor of the mitochondrial permeability transition pore is tuned by the oxidation-reduction state of vicinal thiols. Increase of the gating potential by oxidants and its reversal by reducing agents.

1 reference

12 December 2020

Ceramide and mitochondria in ischemic brain injury.

1 reference

12 December 2020

Menadione-induced apoptosis: roles of cytosolic Ca(2+) elevations and the mitochondrial permeability transition pore

1 reference

12 December 2020

The Ca2+-induced membrane transition in mitochondria. II. Nature of the Ca2+ trigger site

1 reference

12 December 2020

Role of Calcium Signals on Hydrogen Peroxide-Induced Apoptosis in Human Myeloid HL-60 Cells

1 reference

12 December 2020

Structural changes of mitochondria related to apoptosis: swelling and megamitochondria formation.

1 reference

12 December 2020

High throughput fluorescence assays for the measurement of mitochondrial activity in intact human neuroblastoma cells

1 reference

12 December 2020

Inhibition by cyclosporin A of a Ca2+-dependent pore in heart mitochondria activated by inorganic phosphate and oxidative stress

1 reference

12 December 2020

Inhibitors of membrane transport system for organic anions block fura-2 excretion from PC12 and N2A cells

1 reference

12 December 2020

Identifiers

DOI

10.1038/NPROT.2016.064

1 reference

11 May 2018

PubMed ID

27172167

1 reference

11 May 2018