Measurements of ligand bias and functional affinity. (Q53119499)

11 May 2018

title

Measurements of ligand bias and functional affinity. (English)

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11 May 2018

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2

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11 May 2018

author name string

Terry Kenakin

series ordinal

1

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11 May 2018

publication date

17 May 2013

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11 May 2018

Nature Reviews Drug Discovery

published in

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11 May 2018

volume

12

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issue

6

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page(s)

483

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11 May 2018

https://scigraph.springernature.com/pub.10.1038/nrd3954-c2

exact match

0 references

cites work

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Imprecision in presentation of binding studies

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Structure of a nanobody-stabilized active state of the β(2) adrenoceptor

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Galpha-subunits differentially alter the conformation and agonist affinity of kappa-opioid receptors

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An operational model of pharmacological agonism: the effect of E/[A] curve shape on agonist dissociation constant estimation

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Divergent agonist selectivity in activating β1- and β2-adrenoceptors for G-protein and arrestin coupling.

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Estimation of agonist activity at G protein-coupled receptors: analysis of M2 muscarinic receptor signaling through Gi/o,Gs, and G15.

31 March 2020

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Operational models of pharmacological agonism.

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PubMed

https://pubmed.ncbi.nlm.nih.gov/23681003

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Quantifying biased agonism: understanding the links between affinity and efficacy.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23681003

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRD3954-C2

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11 May 2018

1 reference

11 May 2018