A total synthesis of spirastrellolide A methyl ester. (Q53119684)

11 May 2018

title

A total synthesis of spirastrellolide A methyl ester. (English)

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11 May 2018

5

Alois Fürstner

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11 May 2018

Alexander Arlt

1

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11 May 2018

Stefan Benson

series ordinal

2

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11 May 2018

Saskia Schulthoff

series ordinal

3

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11 May 2018

Barbara Gabor

series ordinal

4

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11 May 2018

language of work or name

English

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publication date

18 February 2013

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11 May 2018

Chemistry—A European Journal

published in

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11 May 2018

volume

19

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11 May 2018

issue

11

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11 May 2018

page(s)

3596-3608

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11 May 2018

Spirastrellolide A, An Antimitotic Macrolide Isolated from the Caribbean Marine Sponge Spirastrella coccinea

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Isolation of spirastrellolides A and B from a marine sponge Epipolasis sp. and their cytotoxic activities.

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Synthesis of the bis-spiroacetal C25-C40 moiety of the antimitotic agent spirastrellolide B using a bis-dithiane deprotection/spiroacetalisation sequence.

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Spirastrellolide B: construction of the C(26)-C(40) northern hemisphere and a related [5,5,7]-bis-spiroketal analogue

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Synthesis and stereochemical determination of the spirastrellolides

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Practical new silyloxy-based alkyne metathesis catalysts with optimized activity and selectivity profiles

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Mechanistic investigation leads to a synthetic improvement in the hydrolytic kinetic resolution of terminal epoxides

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19 October 2022

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Identifiers

DOI

10.1002/CHEM.201203965

1 reference

11 May 2018

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11 May 2018