Inhibition of the expression of TGF-β1 and CTGF in human mesangial cells by exendin-4, a glucagon-like peptide-1 receptor agonist. (Q53151512)

11 May 2018

title

Inhibition of the expression of TGF-β1 and CTGF in human mesangial cells by exendin-4, a glucagon-like peptide-1 receptor agonist. (English)

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11 May 2018

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Wenbin Li

1

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11 May 2018

Meiyu Cui

2

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11 May 2018

Yong Wei

3

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11 May 2018

Xianglei Kong

4

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11 May 2018

Lijun Tang

5

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11 May 2018

Dongmei Xu

6

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11 May 2018

publication date

2 August 2012

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11 May 2018

Cellular Physiology and Biochemistry

published in

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11 May 2018

volume

30

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11 May 2018

issue

3

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11 May 2018

page(s)

749-757

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11 May 2018

CTGF expression in mesangial cells: involvement of SMADs, MAP kinase, and PKC.

cites work

1 reference

Connective tissue growth factor: what's in a name?

21 January 2018

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Transforming growth factor-beta and connective tissue growth factor: key cytokines in scleroderma pathogenesis

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Role of connective tissue growth factor in the pathogenesis of diabetic nephropathy

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Connective tissue growth factor in tubulointerstitial injury of diabetic nephropathy

21 January 2018

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In vitro evidence for differential involvement of CTGF, TGFbeta, and PDGF-BB in mesangial response to injury

21 January 2018

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Inhibition of the Jak/STAT signaling pathway prevents the high glucose-induced increase in tgf-beta and fibronectin synthesis in mesangial cells.

21 January 2018

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The control of ccn2 (ctgf) gene expression in normal and scleroderma fibroblasts

21 January 2018

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Cardioprotective and vasodilatory actions of glucagon-like peptide 1 receptor are mediated through both glucagon-like peptide 1 receptor-dependent and -independent pathways

21 January 2018

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Effects of glucagon-like peptide-1 on endothelial function in type 2 diabetes patients with stable coronary artery disease.

21 January 2018

1 reference

Long-term treatment of glucagon-like peptide-1 analog exendin-4 ameliorates diabetic nephropathy through improving metabolic anomalies in db/db mice.

21 January 2018

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The biology of incretin hormones

21 January 2018

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Glucagon-like peptide-1 receptor agonist ameliorates renal injury through its anti-inflammatory action without lowering blood glucose level in a rat model of type 1 diabetes

21 January 2018

1 reference

Effects of DPP-4 inhibitors on the heart in a rat model of uremic cardiomyopathy

21 January 2018

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Glucagon-like peptide 1 prevents reactive oxygen species-induced endothelial cell senescence through the activation of protein kinase A.

21 January 2018

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Hyperglycemia and diabetic kidney disease. The case for transforming growth factor-beta as a key mediator

21 January 2018

1 reference

Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransforming growth factor-beta antibody in db/db diabetic mice

21 January 2018

1 reference

Temporal expression profile and distribution pattern indicate a role of connective tissue growth factor (CTGF/CCN-2) in diabetic nephropathy in mice

21 January 2018

1 reference

Connective tissue growth factor: a mediator of TGF-beta action on fibroblasts

21 January 2018

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Therapeutic potential of angiostatin in diabetic nephropathy

21 January 2018

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Synthetic exendin-4 (exenatide) significantly reduces postprandial and fasting plasma glucose in subjects with type 2 diabetes

21 January 2018

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Insulinotropic actions of exendin-4 and glucagon-like peptide-1 in vivo and in vitro

21 January 2018

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Exendin-4 normalized postcibal glycemic excursions in type 1 diabetes

21 January 2018

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Exendin-4 decelerates food intake, weight gain, and fat deposition in Zucker rats

21 January 2018

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Functional expression of the rat glucagon-like peptide-I receptor, evidence for coupling to both adenylyl cyclase and phospholipase-C.

21 January 2018

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Dose-response for glycaemic and metabolic changes 28 days after single injection of long-acting release exenatide in diabetic fatty Zucker rats

21 January 2018

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Secretion of collagen type IV by human renal fibroblasts is increased by high glucose via a TGF-beta-independent pathway

21 January 2018

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The mitogen-activated protein kinase Erk5 mediates human mesangial cell activation.

21 January 2018

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Minireview: Glucagon-like peptides regulate cell proliferation and apoptosis in the pancreas, gut, and central nervous system

21 January 2018

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Inhibition of monocyte adhesion to endothelial cells and attenuation of atherosclerotic lesion by a glucagon-like peptide-1 receptor agonist, exendin-4.

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1159/000341454

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11 May 2018

PubMed ID

22890152

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11 May 2018