Silencing Poly (ADP-Ribose) glycohydrolase (PARG) expression inhibits growth of human colon cancer cells in vitro via PI3K/Akt/NFκ-B pathway. (Q53237156)

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scientific article published on 30 June 2011

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English	Silencing Poly (ADP-Ribose) glycohydrolase (PARG) expression inhibits growth of human colon cancer cells in vitro via PI3K/Akt/NFκ-B pathway.	scientific article published on 30 June 2011

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/21713600

Silencing Poly (ADP-Ribose) glycohydrolase (PARG) expression inhibits growth of human colon cancer cells in vitro via PI3K/Akt/NFκ-B pathway. (English)

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Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/21713600

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author name string

Nilufer Jasmine Selimah Fauzee

1

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/21713600

Qiaozhuan Li

2

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/21713600

Ya-Lan Wang

3

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/21713600

Juan Pan

4

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Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/21713600

publication date

30 June 2011

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Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/21713600

Pathology and Oncology Research

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Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/21713600

18

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Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/21713600

2

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/21713600

191-199

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/21713600

Poly(ADP-ribose) glycohydrolase silencing protects against H2O2-induced cell death

1 reference

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Failure to degrade poly(ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality

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Spatial and functional relationship between poly(ADP-ribose) polymerase-1 and poly(ADP-ribose) glycohydrolase in the brain

1 reference

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Human poly(ADP-ribose) glycohydrolase (PARG) gene and the common promoter sequence it shares with inner mitochondrial membrane translocase 23 (TIM23)

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The roles of poly(ADP-ribose)-metabolizing enzymes in alkylation-induced cell death.

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The role of Akt and mitogen-activated protein kinase systems in the protective effect of poly(ADP-ribose) polymerase inhibition in Langendorff perfused and in isoproterenol-damaged rat hearts

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Oncogenic PI3K deregulates transcription and translation

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Id-1 activation of PI3K/Akt/NFkappaB signaling pathway and its significance in promoting survival of esophageal cancer cells

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The PI 3-kinase/Akt signaling pathway is activated due to aberrant Pten expression and targets transcription factors NF-kappaB and c-Myc in pancreatic cancer cells

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NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

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The therapeutic potential of poly(ADP-ribose) polymerase inhibitors

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Poly(ADP-ribose) polymerase inhibition down-regulates expression of metastasis-related genes in CT26 colon carcinoma cells

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Drosophila poly(ADP-ribose) glycohydrolase mediates chromatin structure and SIR2-dependent silencing

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Dual role of poly(ADP-ribose) glycohydrolase in the regulation of cell death in oxidatively stressed A549 cells

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PARP and PARG inhibitors--new therapeutic targets in cancer treatment

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NF-kappaB in cancer: from innocent bystander to major culprit

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Regulation of kinase cascades and transcription factors by a poly(ADP-ribose) polymerase-1 inhibitor, 4-hydroxyquinazoline, in lipopolysaccharide-induced inflammation in mice

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Critical role of PI3-kinase/Akt activation in the PARP inhibitor induced heart function recovery during ischemia-reperfusion

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IKKbeta/NF-kappaB activation causes severe muscle wasting in mice

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Induction of NF-kappa B-like activity by platelet-derived growth factor in mouse fibroblasts

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NF-kappaB mediates FGF signal regulation of msx-1 expression.

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NF-kappaB and the immune response

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Akt-mediated regulation of NFkappaB and the essentialness of NFkappaB for the oncogenicity of PI3K and Akt

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21 January 2018

The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells

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21 January 2018

Effect of hydrogen sulfide on the phosphatidylinositol 3-kinase-protein kinase B pathway and on caerulein-induced cytokine production in isolated mouse pancreatic acinar cells

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Attenuation of cardiac dysfunction by HSPA12B in endotoxin-induced sepsis in mice through a PI3K-dependent mechanism

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Targeting Akt in cancer therapy

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

The phosphatidylinositol 3-kinase/Akt pathway negatively regulates Nod2-mediated NF-kappaB pathway

1 reference

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12 December 2020

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The Role of NF- B in Protein Breakdown in Immobilization, Aging, and Exercise: From Basic Processes to Promotion of Health

1 reference

https://pubmed.ncbi.nlm.nih.gov/21713600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S12253-011-9428-1

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/21713600

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/21713600

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