A pharmacokinetic model of the intracellular dosimetry of inhaled nickel. (Q53334206)

13 May 2018

title

A pharmacokinetic model of the intracellular dosimetry of inhaled nickel. (English)

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13 May 2018

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7

Harvey J Clewell

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13 May 2018

author name string

C Eric Hack

1

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Tammie R Covington

2

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Greg Lawrence

3

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Annette M Shipp

4

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Robinan Gentry

5

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Janice Yager

6

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publication date

1 March 2007

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Journal of Toxicology and Environmental Health Part A

published in

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volume

70

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issue

5

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page(s)

445-464

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Cytoplasmic dissolution of phagocytized crystalline nickel sulfide particles: a prerequisite for nuclear uptake of nickel.

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Surface reduction of amorphous NiS particles potentiates their phagocytosis and subsequent induction of morphological transformation in Syrian hamster embryo cells

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Uptake and biological transformation of beta NiS and alpha Ni3S2 by human embryonic pulmonary epithelial cells (L132) in culture

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Effects of amorphous and crystalline nickel sulfide on induction of interferons-alpha/beta and -gamma and interleukin-2.

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Senescence of nickel-transformed cells by an X chromosome: possible epigenetic control

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The role of oxidative processes in metal carcinogenesis

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Dissolution half-times of nickel compounds in water, rat serum, and renal cytosol.

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Molecular biology of deregulated gene expression in transformed C3H/10T1/2 mouse embryo cell lines induced by specific insoluble carcinogenic nickel compounds

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Respiratory carcinogenicity assessment of soluble nickel compounds

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Carcinogenicity assessment of selected nickel compounds

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Induction of proliferin gene expression by diverse chemical agents that promote morphological transformation in C3H/10T1/2 cultures

21 January 2018

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DNA-protein cross-links induced by nickel compounds in intact cultured mammalian cells.

21 January 2018

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Transformation of rat tracheal epithelial cells to immortal growth variants by particulate and soluble nickel compounds

21 January 2018

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Loss of thrombospondin transcriptional activity in nickel-transformed cells

21 January 2018

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The role of hypoxia-inducible signaling pathway in nickel carcinogenesis

21 January 2018

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Incidence and localization of sister chromatid exchanges induced by nickel and chromium compounds

21 January 2018

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Generation of free radicals from lipid hydroperoxides by Ni2+ in the presence of oligopeptides

21 January 2018

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Generation of Free Radicals in Reactions of Ni (II)-thiol

21 January 2018

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Metal carcinogenesis: mechanistic implications

21 January 2018

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Physicochemical characteristics and biological effects of nickel oxides.

21 January 2018

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Interactions of alpha Ni3S2 with guinea pig alveolar macrophages and liberation of inflammatory mediators

21 January 2018

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Chronic inhalation of nickel oxide and cigarette smoke by hamsters

21 January 2018

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DNA strand breaks and poly (ADP-ribose) polymerase activation induced by crystalline nickel subsulfide in MRC-5 lung fibroblast cells

21 January 2018

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Molecular mechanisms in nickel carcinogenesis: modeling Ni(II) binding site in histone H4.

21 January 2018

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Toxicity and carcinogenicity of nickel compounds

21 January 2018

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Differences in surface properties of amorphous and crystalline metal sulfides may explain their toxicological potency

21 January 2018

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Using Alternative Comparison Populations to Assess Occupation-Related Mortality Risk

21 January 2018

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10.1080/15287390600870726

21 January 2018

Identifiers

DOI

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13 May 2018

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13 May 2018