Alzheimer's disease drug discovery targeted to the APP mRNA 5'untranslated region. (Q53354243)

13 May 2018

title

Alzheimer's disease drug discovery targeted to the APP mRNA 5'untranslated region. (English)

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13 May 2018

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5

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Jack T Rogers

Jack T Rogers

1

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Rudolph E. Tanzi

6

Rudolph E Tanzi

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Robert D. Moir

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Robert Moir

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Sandra M Payton

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Sandra M Payton

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Jeffrey R. Seemann

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Jeffrey D Randall

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Nigel H Greig

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Nigel Greig

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Debomoy Lahiri

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Debomoy K Lahiri

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Seiichi Nagano

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Seiichi Nagano

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author name string

Paul S Eder

3

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Xudong Huang

4

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Amanda Venti

7

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Tony Giordano

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Catherine M Cahill

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Satinder Singh Sarang

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Steven R Gullans

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publication date

1 August 2002

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Journal of Molecular Neuroscience

published in

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volume

19

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issue

1-2

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page(s)

77-82

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Ibuprofen suppresses plaque pathology and inflammation in a mouse model for Alzheimer's disease.

cites work

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Phenserine regulates translation of beta -amyloid precursor protein mRNA by a putative interleukin-1 responsive element, a target for drug development

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Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

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Iron depletion or chelation reduces ischemia/reperfusion-induced edema in gerbil brains

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Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695.

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Promoter activity of the gene encoding the beta-amyloid precursor protein is up-regulated by growth factors, phorbol ester, retinoic acid and interleukin-1.

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Pharmacological modulation of Alzheimer's beta-amyloid precursor protein levels in the CSF of rats with forebrain cholinergic system lesions

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Structure of the human alpha 1-acid glycoprotein gene: sequence homology with other human acute phase protein genes

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12 December 2020

Iron-regulatory proteins, iron-responsive elements and ferritin mRNA translation

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12 December 2020

On finding all suboptimal foldings of an RNA molecule

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12 December 2020

Synthesis of novel phenserine-based-selective inhibitors of butyrylcholinesterase for Alzheimer's disease.

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12 December 2020

Intramuscular desferrioxamine in patients with Alzheimer's disease

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12 December 2020

A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

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12 December 2020

Translation of the alzheimer amyloid precursor protein mRNA is up-regulated by interleukin-1 through 5'-untranslated region sequences.

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12 December 2020

10.1007/S12031-002-0014-6

Identifiers

DOI

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13 May 2018

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13 May 2018