Soluble TNF-alpha but not transmembrane TNF-alpha sensitizes T cells for enhanced activation-induced cell death. (Q53377749)

13 May 2018

title

Soluble TNF-alpha but not transmembrane TNF-alpha sensitizes T cells for enhanced activation-induced cell death. (English)

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13 May 2018

main subject

TNF

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transmembrane protein

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author

Christoph Mueller

7

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13 May 2018

author name string

Stefan Müller

1

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13 May 2018

Silvia Rihs

2

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13 May 2018

Johanna M Dayer Schneider

3

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13 May 2018

Bruno E Paredes

4

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13 May 2018

Ingeborg Seibold

5

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13 May 2018

Thomas Brunner

6

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13 May 2018

language of work or name

English

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publication date

1 November 2009

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13 May 2018

European Journal of Immunology

published in

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13 May 2018

volume

39

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13 May 2018

issue

11

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13 May 2018

page(s)

3171-3180

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13 May 2018

Transmembrane TNF induces an efficient cell-mediated immunity and resistance to Mycobacterium bovis bacillus Calmette-Guérin infection in the absence of secreted TNF and lymphotoxin-alpha.

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Prolonged exposure of T cells to TNF down-regulates TCR zeta and expression of the TCR/CD3 complex at the cell surface.

21 January 2018

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A membrane form of TNF-alpha presented by exosomes delays T cell activation-induced cell death

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TNF-alpha is a critical negative regulator of type 1 immune activation during intracellular bacterial infection

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Regulation of Fas ligand-induced apoptosis by TNF.

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Intestinal intraepithelial lymphocytes exert potent protective cytotoxic activity during an acute virus infection.

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On the role of tumor necrosis factor and receptors in models of multiorgan failure, rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease

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7 January 2021

Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha

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7 January 2021

A nonsecretable cell surface mutant of tumor necrosis factor (TNF) kills by cell-to-cell contact

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7 January 2021

Noncleavable transmembrane mouse tumor necrosis factor-alpha (TNFalpha) mediates effects distinct from those of wild-type TNFalpha in vitro and in vivo

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7 January 2021

A murine transmembrane tumor necrosis factor (TNF) transgene induces arthritis by cooperative p55/p75 TNF receptor signaling

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In vivo evidence for a functional role of both tumor necrosis factor (TNF) receptors and transmembrane TNF in experimental hepatitis

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Membrane-bound TNF supports secondary lymphoid organ structure but is subservient to secreted TNF in driving autoimmune inflammation.

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Protection against a lethal dose of endotoxin by an inhibitor of tumour necrosis factor processing

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TNF is a potent anti-inflammatory cytokine in autoimmune-mediated demyelination.

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Effect of tumor necrosis factor alpha on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process

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T cell-derived TNF down-regulates acute airway response to endotoxin

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7 January 2021

Studies of T-cell activation in chronic inflammation

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Chronic tumor necrosis factor alters T cell responses by attenuating T cell receptor signaling

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7 January 2021

T cell receptor zeta reconstitution fails to restore responses of T cells rendered hyporesponsive by tumor necrosis factor alpha

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7 January 2021

Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas.

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Induction of apoptosis in mature T cells by tumour necrosis factor

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7 January 2021

Local Fas/APO-1 (CD95) ligand-mediated tumor cell killing in vivo

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7 January 2021

Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice

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7 January 2021

CD4+ T cells that express high levels of CD45RB induce wasting disease when transferred into congenic severe combined immunodeficient mice. Disease development is prevented by cotransfer of purified CD4+ T cells

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7 January 2021

Genetic models for CNS inflammation

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7 January 2021

Transmembrane tumor necrosis factor is a potent inducer of colitis even in the absence of its secreted form

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7 January 2021

Uncoupling the proinflammatory from the immunosuppressive properties of tumor necrosis factor (TNF) at the p55 TNF receptor level: implications for pathogenesis and therapy of autoimmune demyelination

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7 January 2021

Prevention of autoimmune diabetes mellitus in NOD mice by transgenic expression of soluble tumor necrosis factor receptor p55

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7 January 2021

Local expression of TNFalpha in neonatal NOD mice promotes diabetes by enhancing presentation of islet antigens

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7 January 2021

Recombinant human tumor necrosis factor alpha suppresses autoimmune diabetes in nonobese diabetic mice

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7 January 2021

Prevention of diabetes in nonobese diabetic mice by tumor necrosis factor (TNF): similarities between TNF-alpha and interleukin 1.

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7 January 2021

Local expression of transgene encoded TNF alpha in islets prevents autoimmune diabetes in nonobese diabetic (NOD) mice by preventing the development of auto-reactive islet-specific T cells

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7 January 2021

Involvement of TNF in limiting liver pathology and promoting parasite survival during schistosome infection

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7 January 2021

Massive expansion of antigen-specific CD8+ T cells during an acute virus infection

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7 January 2021

Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim.

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7 January 2021

Lack of TNFR2 expression by CD4(+) T cells exacerbates experimental colitis

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7 January 2021

Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent

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7 January 2021

T-cell signalling and autoimmunity: molecular mechanisms of disease

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7 January 2021

Nonlymphocyte-derived tumor necrosis factor is required for induction of colitis in recombination activating gene (RAG)2(-/-) mice upon transfer of CD4(+)CD45RB(hi) T cells

1 reference

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7 January 2021

Identifiers

DOI

10.1002/EJI.200939554

1 reference

13 May 2018

1 reference

13 May 2018