Development of PAC-14028, a novel transient receptor potential vanilloid type 1 (TRPV1) channel antagonist as a new drug for refractory skin diseases. (Q53381596)

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English	Development of PAC-14028, a novel transient receptor potential vanilloid type 1 (TRPV1) channel antagonist as a new drug for refractory skin diseases.	scientific article

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scholarly article

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/22477184

Development of PAC-14028, a novel transient receptor potential vanilloid type 1 (TRPV1) channel antagonist as a new drug for refractory skin diseases. (English)

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/22477184

1

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/22477184

author name string

Young-Ho Park

2

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/22477184

publication date

1 March 2012

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/22477184

Archives of Pharmacal Research

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Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/22477184

35

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/22477184

3

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/22477184

393-396

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/22477184

https://scigraph.springernature.com/pub.10.1007/s12272-012-0321-6

0 references

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1 reference

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Impaired nociception and pain sensation in mice lacking the capsaicin receptor

1 reference

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The effects of the TRPV1 antagonist SB-705498 on TRPV1 receptor-mediated activity and inflammatory hyperalgesia in humans

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https://api.crossref.org/works/10.1007%2FS12272-012-0321-6

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Contributions of different modes of TRPV1 activation to TRPV1 antagonist-induced hyperthermia

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https://api.crossref.org/works/10.1007%2FS12272-012-0321-6

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Pharmacological blockade of the vanilloid receptor TRPV1 elicits marked hyperthermia in humans

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https://api.crossref.org/works/10.1007%2FS12272-012-0321-6

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Attenuated fever response in mice lacking TRPV1

1 reference

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Synthesis of N,N',N"-trisubstituted thiourea derivatives and their antagonist effect on the vanilloid receptor

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0321-6

21 January 2018

Oral and topical pharmacokinetic studies of a novel TRPV1 antagonist, PAC-14028 in rats and minipigs using liquid chromatography/tandem mass spectrometric method.

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0321-6

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Release of multiple tachykinins from capsaicin-sensitive sensory nerves in the lung by bradykinin, histamine, dimethylphenyl piperazinium, and vagal nerve stimulation

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Neurophysiological, neuroimmunological, and neuroendocrine basis of pruritus

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Novel potent antagonists of transient receptor potential channel, vanilloid subfamily member 1: structure-activity relationship of 1,3-diarylalkyl thioureas possessing new vanilloid equivalents

1 reference

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The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept

1 reference

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International Union of Basic and Clinical Pharmacology. LXXVI. Current progress in the mammalian TRP ion channel family

1 reference

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Antipruritic Effects of TRPV1 Antagonist in Murine Atopic Dermatitis and Itching Models

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Identifiers

10.1007/S12272-012-0321-6

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/22477184

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/22477184

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