Somatostatin genetic variants modify the risk for Alzheimer's disease among Finnish patients. (Q53389768)

13 May 2018

title

Somatostatin genetic variants modify the risk for Alzheimer's disease among Finnish patients. (English)

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13 May 2018

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6

Hilkka Soininen

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13 May 2018

Saila Vepsäläinen

1

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13 May 2018

Seppo Helisalmi

2

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13 May 2018

Anne M Koivisto

3

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13 May 2018

Toni Tapaninen

4

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13 May 2018

Mikko Hiltunen

5

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publication date

9 November 2007

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13 May 2018

published in

Journal of Neurology

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13 May 2018

volume

254

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13 May 2018

issue

11

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13 May 2018

page(s)

1504-1508

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https://scigraph.springernature.com/pub.10.1007/s00415-007-0539-2

exact match

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cites work

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APOE epsilon4 allele is associated with reduced cerebrospinal fluid levels of Abeta42.

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Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

21 January 2018

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Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium

21 January 2018

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Somatostatin regulates brain amyloid beta peptide Abeta42 through modulation of proteolytic degradation.

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Expanded Genomewide Scan Implicates a Novel Locus at 3q28 Among Caribbean Hispanics With Familial Alzheimer Disease

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The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

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Apolipoprotein E, epsilon 4 allele as a major risk factor for sporadic early and late-onset forms of Alzheimer's disease: analysis of the 19q13.2 chromosomal region.

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Cerebrospinal fluid beta-amyloid1-42 and tau in control subjects at risk for Alzheimer's disease: the effect of APOE epsilon4 allele

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High cerebrospinal fluid tau and low amyloid beta42 levels in the clinical diagnosis of Alzheimer disease and relation to apolipoprotein E genotype.

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The structure of haplotype blocks in the human genome

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Clinical and neuropsychological characteristics in familial and sporadic Alzheimer's disease: relation to apolipoprotein E polymorphism

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Somatostatin in the central nervous system: physiology and pathological modifications

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Somatostatin in Alzheimer's disease and depression

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Reduced cholinesterase activity and somatostatin-like immunoreactivity in the cerebrospinal fluid of patients with dementia of the Alzheimer type.

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Loss of somatostatin-like immunoreactivity in the frontal cortex of Alzheimer patients carrying the apolipoprotein epsilon 4 allele.

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Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

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Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

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10.1007/S00415-007-0539-2

Identifiers

DOI

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13 May 2018

PubMed ID

17987251

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13 May 2018