Small molecule inhibitors that discriminate between protein arginine N-methyltransferases PRMT1 and CARM1. (Q53404642)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21952734%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

Small molecule inhibitors that discriminate between protein arginine N-methyltransferases PRMT1 and CARM1 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21952734%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21952734%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Stephen G Ward

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21952734%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

author name string

Richard A Pike

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21952734%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Richard V Parry

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21952734%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Wei Hong

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21952734%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Usama A Muhsen

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21952734%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

publication date

27 September 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21952734%20AND%20SRC:MED&resulttype=core&format=json

Organic and Biomolecular Chemistry

13 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21952734%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21952734%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

issue

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21952734%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

page(s)

7814-7821

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21952734%20AND%20SRC:MED&resulttype=core&format=json

Protein methyltransferases as a target class for drug discovery

13 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

Chemical probes for histone-modifying enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

Chemical mechanisms of histone lysine and arginine modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

Arginine methylation at a glance

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

Increased protein arginine methylation in chronic hypoxia: role of protein arginine methyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

Methylation of Tat by PRMT6 regulates human immunodeficiency virus type 1 gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

CD28 costimulatory signal induces protein arginine methylation in T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

Dysregulation of PRMT1 and PRMT6, Type I arginine methyltransferases, is involved in various types of human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

Global histone modification patterns predict risk of prostate cancer recurrence

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

Involvement of arginine methyltransferase CARM1 in androgen receptor function and prostate cancer cell viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

Aberrant expression of CARM1, a transcriptional coactivator of androgen receptor, in the development of prostate carcinoma and androgen-independent status

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

Coactivator-associated arginine methyltransferase 1 (CARM1) is a positive regulator of the Cyclin E1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

A combinatorial approach to characterize the substrate specificity of protein arginine methyltransferase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

A chloroacetamidine-based inactivator of protein arginine methyltransferase 1: design, synthesis, and in vitro and in vivo evaluation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

Nη-substituted arginyl peptide inhibitors of protein arginine N-methyltransferases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

Small molecule regulators of protein arginine methyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

Discovery and mechanistic study of a class of protein arginine methylation inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

Effects of a novel arginine methyltransferase inhibitor on T-helper cell cytokine production

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

Design, synthesis and biological evaluation of carboxy analogues of arginine methyltransferase inhibitor 1 (AMI-1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

Small molecule inhibitors of histone arginine methyltransferases: homology modeling, molecular docking, binding mode analysis, and biological evaluations

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

Pyrazole inhibitors of coactivator associated arginine methyltransferase 1 (CARM1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

N-Benzyl-1-heteroaryl-3-(trifluoromethyl)-1H-pyrazole-5-carboxamides as inhibitors of co-activator associated arginine methyltransferase 1 (CARM1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

Optimization of pyrazole inhibitors of Coactivator Associated Arginine Methyltransferase 1 (CARM1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

Benzo[d]imidazole inhibitors of Coactivator Associated Arginine Methyltransferase 1 (CARM1)--Hit to Lead studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

1,2-Diamines as inhibitors of co-activator associated arginine methyltransferase 1 (CARM1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

Structural basis for CARM1 inhibition by indole and pyrazole inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

Toward the development of potent and selective bisubstrate inhibitors of protein arginine methyltransferases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

Structural chemistry of the histone methyltransferases cofactor binding site.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

Synthesis and evaluation of mono-, di-, and trifluoroethenyl-GABA derivatives as GABA-T inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

Development of novel bisubstrate-type inhibitors of histone methyltransferase SET7/9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

Structure of the Predominant Protein Arginine Methyltransferase PRMT1 and Analysis of Its Binding to Substrate Peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

Mechanistic studies on transcriptional coactivator protein arginine methyltransferase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

Crystal structure of the conserved core of protein arginine methyltransferase PRMT3

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

Functional insights from structures of coactivator-associated arginine methyltransferase 1 domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

The Blue Obelisk-interoperability in chemical informatics

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

CAVER: a new tool to explore routes from protein clefts, pockets and cavities

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

Targeting epigenetic modifiers: Inhibitors of histone methyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1OB06100C

21 January 2018

Identifiers

DOI

10.1039/C1OB06100C

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21952734%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference