Pharmacological targeting of C5a receptors during organ preservation improves kidney graft survival. (Q53475097)

14 May 2018

title

Pharmacological targeting of C5a receptors during organ preservation improves kidney graft survival. (English)

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14 May 2018

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A G Lewis

1

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14 May 2018

G Köhl

2

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14 May 2018

Q Ma

3

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14 May 2018

P Devarajan

4

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14 May 2018

J Köhl

5

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14 May 2018

publication date

26 May 2008

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14 May 2018

Clinical and Experimental Immunology

published in

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14 May 2018

volume

153

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14 May 2018

issue

1

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14 May 2018

page(s)

117-126

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14 May 2018

Decay accelerating factor can control T cell differentiation into IFN-gamma-producing effector cells via regulating local C5a-induced IL-12 production

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CCL19-IgG prevents allograft rejection by impairment of immune cell trafficking.

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Update on mechanisms of ischemic acute kidney injury

25 August 2018

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A regulatory role for the C5a anaphylatoxin in type 2 immunity in asthma

25 August 2018

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Delayed graft function: a dilemma in renal transplantation

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Mannan-binding lectin recognizes structures on ischaemic reperfused mouse kidneys and is implicated in tissue injury

25 August 2018

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C5a negatively regulates toll-like receptor 4-induced immune responses

25 August 2018

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Role of C5a in inflammatory responses

25 August 2018

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Delayed graft function in kidney transplantation

25 August 2018

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The mannose-binding lectin-pathway is involved in complement activation in the course of renal ischemia-reperfusion injury

25 August 2018

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Initiation of complement activation following oxidative stress. In vitro and in vivo observations

25 August 2018

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25 August 2018

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C5a mutants are potent antagonists of the C5a receptor (CD88) and of C5L2: position 69 is the locus that determines agonism or antagonism

25 August 2018

1 reference

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Nontransgenic Hyperexpression of a Complement Regulator in Donor Kidney Modulates Transplant Ischemia/Reperfusion Damage, Acute Rejection, and Chronic Nephropathy

25 August 2018

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Role of the complement system in rejection.

25 August 2018

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B cell deficiency confers protection from renal ischemia reperfusion injury.

25 August 2018

1 reference

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Complement factor C5a mediates renal ischemia-reperfusion injury independent from neutrophils.

25 August 2018

1 reference

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Cell death induced by acute renal injury: a perspective on the contributions of apoptosis and necrosis

25 August 2018

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Lack of a functional alternative complement pathway ameliorates ischemic acute renal failure in mice

25 August 2018

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A small molecule C5a receptor antagonist protects kidneys from ischemia/reperfusion injury in rats

25 August 2018

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25 August 2018

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Neutralization of Gro alpha and macrophage inflammatory protein-2 attenuates renal ischemia/reperfusion injury

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2432105

Inhibiting the complement system does not reduce injury in renal ischemia reperfusion

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2432105

Enhanced expression of complement C5a receptor mRNA in human diseased kidney assessed by in situ hybridization

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2432105

The C5a receptor is expressed by human renal proximal tubular epithelial cells

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2432105

Predominant role for C5b-9 in renal ischemia/reperfusion injury.

25 August 2018

1 reference

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Selection of a C5a receptor antagonist from phage libraries attenuating the inflammatory response in immune complex disease and ischemia/reperfusion injury.

25 August 2018

1 reference

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Hypothesis: is renal allograft rejection initiated by the response to injury sustained during the transplant process?

25 August 2018

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Impaired inflammatory responses in the reverse arthus reaction through genetic deletion of the C5a receptor

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2432105

Delayed graft function: risk factors and implications for renal allograft survival

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2432105

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2432105

A codominant role of Fc gamma RI/III and C5aR in the reverse Arthus reaction

25 August 2018

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12 December 2020

Identification of complement factor 5 as a susceptibility locus for experimental allergic asthma

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12 December 2020

Activation of mitochondrial apoptotic pathways in human renal allografts after ischemiareperfusion injury

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12 December 2020

Mechanisms of ischemic acute renal failure

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12 December 2020

The impact of the quality of initial graft function on cadaver kidney transplants

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12 December 2020

Risk factors for delayed graft function in cadaveric kidney transplantation: a prospective study of renal function and graft survival after preservation with University of Wisconsin solution in multi-organ donors. European Multicenter Study Group.

1 reference

12 December 2020

Involvement of endogenous interleukin-10 and tumor necrosis factor-alpha in renal ischemia-reperfusion injury

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12 December 2020

Therapeutic strategy with a membrane-localizing complement regulator to increase the number of usable donor organs after prolonged cold storage

1 reference

12 December 2020

Preventing renal ischemia-reperfusion injury using small interfering RNA by targeting complement 3 gene

1 reference

12 December 2020

Multicenter analysis of kidney preservation

1 reference

12 December 2020

Protective effects of IL-6 blockade in sepsis are linked to reduced C5a receptor expression

1 reference

12 December 2020

The C5a receptor is expressed in normal renal proximal tubular but not in normal pulmonary or hepatic epithelial cells

1 reference

12 December 2020

10.1111/J.1365-2249.2008.03678.X

Identifiers

DOI

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14 May 2018

0 references

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14 May 2018