Amyloid precursor protein intracellular domain modulates cellular calcium homeostasis and ATP content. (Q53531096)

15 May 2018

title

Amyloid precursor protein intracellular domain modulates cellular calcium homeostasis and ATP content. (English)

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15 May 2018

9

Christian Haass

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15 May 2018

Jochen Herms

10

object named as

Jochen Herms

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15 May 2018

Hans Kretzschmar

8

object named as

Hans A Kretzschmar

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15 May 2018

author name string

Runa Hamid

1

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15 May 2018

Ellen Kilger

2

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15 May 2018

Michael Willem

3

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15 May 2018

Neville Vassallo

4

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15 May 2018

Markus Kostka

5

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15 May 2018

Carsten Bornhövd

6

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15 May 2018

Andreas S Reichert

7

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15 May 2018

language of work or name

English

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publication date

1 August 2007

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15 May 2018

Journal of Neurochemistry

published in

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15 May 2018

volume

102

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issue

4

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page(s)

1264-1275

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15 May 2018

Beta-amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase.

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Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3

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Glycogen synthase kinase-3 beta is highly activated in nuclei and mitochondria

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A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

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Historical review: mitochondria and calcium: ups and downs of an unusual relationship

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Presenilin 1 mutations activate gamma 42-secretase but reciprocally inhibit epsilon-secretase cleavage of amyloid precursor protein (APP) and S3-cleavage of notch

21 January 2018

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Stimulation by calcium ions of pyruvate dehydrogenase phosphate phosphatase

21 January 2018

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Calcium ions and the regulation of NAD+-linked isocitrate dehydrogenase from the mitochondria of rat heart and other tissues

21 January 2018

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Insulin-degrading enzyme rapidly removes the beta-amyloid precursor protein intracellular domain (AICD)

21 January 2018

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Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets

21 January 2018

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The regions of the Fe65 protein homologous to the phosphotyrosine interaction/phosphotyrosine binding domain of Shc bind the intracellular domain of the Alzheimer's amyloid precursor protein

21 January 2018

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APP intracellular domain is increased and soluble Abeta is reduced with diet-induced hypercholesterolemia in a transgenic mouse model of Alzheimer disease

21 January 2018

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Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

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The effect of Ca2+ on the oxidation of glycerol phosphate by blowfly flight-muscle mitochondria.

21 January 2018

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Amyloid, the presenilins and Alzheimer's disease

21 January 2018

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Capacitive calcium entry is directly attenuated by mutant presenilin-1, independent of the expression of the amyloid precursor protein

21 January 2018

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Regulation of mitochondrial pyruvate dehydrogenase activity by tau protein kinase I/glycogen synthase kinase 3beta in brain

21 January 2018

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The intracellular domain of the beta-amyloid precursor protein is stabilized by Fe65 and translocates to the nucleus in a notch-like manner

21 January 2018

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Capacitative calcium entry deficits and elevated luminal calcium content in mutant presenilin-1 knockin mice

21 January 2018

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A physiologic signaling role for the gamma -secretase-derived intracellular fragment of APP.

21 January 2018

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The effects of calcium ions and adenine nucleotides on the activity of pig heart 2-oxoglutarate dehydrogenase complex

21 January 2018

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The beta-amyloid precursor protein functions as a cytosolic anchoring site that prevents Fe65 nuclear translocation

21 January 2018

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Presenilin-1 mutations of leucine 166 equally affect the generation of the Notch and APP intracellular domains independent of their effect on Abeta 42 production

21 January 2018

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Modulation of gene expression and cytoskeletal dynamics by the amyloid precursor protein intracellular domain (AICD)

21 January 2018

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The use of fura-2 for estimating Ca buffers and Ca fluxes.

21 January 2018

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Towards the molecular basis for the regulation of mitochondrial dehydrogenases by calcium ions

21 January 2018

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Activation of GSK-3 and phosphorylation of CRMP2 in transgenic mice expressing APP intracellular domain

21 January 2018

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Presenilin-dependent gamma-secretase processing of beta-amyloid precursor protein at a site corresponding to the S3 cleavage of Notch

21 January 2018

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Potential Link between Amyloid β-Protein 42 and C-terminal Fragment γ 49–99 of β-Amyloid Precursor Protein

21 January 2018

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Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

21 January 2018

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Mutant presenilins disturb neuronal calcium homeostasis in the brain of transgenic mice, decreasing the threshold for excitotoxicity and facilitating long-term potentiation

21 January 2018

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The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease

21 January 2018

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Assessment of mitochondrial polarization status in living cells based on analysis of the spatial heterogeneity of rhodamine 123 fluorescence staining

21 January 2018

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Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations

21 January 2018

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A novel epsilon-cleavage within the transmembrane domain of the Alzheimer amyloid precursor protein demonstrates homology with Notch processing

21 January 2018

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Characterization of a presenilin-mediated amyloid precursor protein carboxyl-terminal fragment gamma. Evidence for distinct mechanisms involved in gamma -secretase processing of the APP and Notch1 transmembrane domains

21 January 2018

1 reference

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10.1111/J.1471-4159.2007.04627.X

21 January 2018

Identifiers

DOI

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15 May 2018

PubMed ID

17763532

1 reference

15 May 2018