High-throughput multi-parameter profiling of electrophysiological drug effects in human embryonic stem cell derived cardiomyocytes using multi-electrode arrays. (Q53555497)

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English	High-throughput multi-parameter profiling of electrophysiological drug effects in human embryonic stem cell derived cardiomyocytes using multi-electrode arrays.	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/24812011

High-throughput multi-parameter profiling of electrophysiological drug effects in human embryonic stem cell derived cardiomyocytes using multi-electrode arrays. (English)

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/24812011

electrophysiology

1 reference

based on heuristic

inferred from title

human embryonic stem cell

1 reference

based on heuristic

inferred from title

author name string

Mike Clements

1

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/24812011

Nick Thomas

2

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/24812011

publication date

8 May 2014

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/24812011

Toxicological Sciences

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/24812011

140

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/24812011

2

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/24812011

445-461

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/24812011

Dynamic monitoring of beating periodicity of stem cell-derived cardiomyocytes as a predictive tool for preclinical safety assessment

1 reference

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Prediction of drug-induced cardiotoxicity using human embryonic stem cell-derived cardiomyocytes

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21 January 2018

In vitro electrophysiological drug testing using human embryonic stem cell derived cardiomyocytes

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFU084

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An evaluation of hERG current assay performance: Translating preclinical safety studies to clinical QT prolongation

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Estimating the risk of drug-induced proarrhythmia using human induced pluripotent stem cell-derived cardiomyocytes

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Refining the human iPSC-cardiomyocyte arrhythmic risk assessment model

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The electrophysiological effects of cardiac glycosides in human iPSC-derived cardiomyocytes and in guinea pig isolated hearts

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21 January 2018

Comparison of electrophysiological data from human-induced pluripotent stem cell-derived cardiomyocytes to functional preclinical safety assays

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Electrophysiological characterization of cardiomyocytes derived from human induced pluripotent stem cells

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MICE models: superior to the HERG model in predicting Torsade de Pointes

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High purity human-induced pluripotent stem cell-derived cardiomyocytes: electrophysiological properties of action potentials and ionic currents.

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In vitro preclinical cardiac assessment of tolterodine and terodiline: multiple factors predict the clinical experience

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Micro-electrode arrays in cardiac safety pharmacology: a novel tool to study QT interval prolongation

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Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk

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21 January 2018

The action potential and comparative pharmacology of stem cell-derived human cardiomyocytes

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21 January 2018

Phenotypic profiling of structural cardiotoxins in vitro reveals dependency on multiple mechanisms of toxicity

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21 January 2018

Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFU084

21 January 2018

Human induced pluripotent stem cells and their use in drug discovery for toxicity testing

1 reference

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21 January 2018

Developmental toxicity testing in the 21st century: the sword of Damocles shattered by embryonic stem cell assays?

1 reference

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21 January 2018

Mechanism of block and identification of the verapamil binding domain to HERG potassium channels

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21 January 2018

Identifiers

10.1093/TOXSCI/KFU084

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/24812011

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/24812011

ResearchGate publication ID

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