Insulin reverses growth hormone-induced homologous desensitization. (Q53621632)

16 May 2018

title

Insulin reverses growth hormone-induced homologous desensitization. (English)

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16 May 2018

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Jie Xu

1

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16 May 2018

Zhongyu Liu

series ordinal

2

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16 May 2018

Thomas L Clemens

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3

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16 May 2018

Joseph L Messina

series ordinal

4

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16 May 2018

language of work or name

English

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publication date

22 May 2006

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16 May 2018

Journal of Biological Chemistry

number of pages

13

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based on heuristic

inferred from page(s)

published in

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16 May 2018

volume

281

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16 May 2018

issue

31

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16 May 2018

page(s)

21594-21606

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16 May 2018

Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase

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Insulin receptor substrate-1 enhances growth hormone-induced proliferation

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Evidence for an Endogenous Ultradian Rhythm Governing Growth Hormone Secretion in the Rat

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Growth hormone activation of Stat 1, Stat 3, and Stat 5 in rat liver. Differential kinetics of hormone desensitization and growth hormone stimulation of both tyrosine phosphorylation and serine/threonine phosphorylation

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Intermittent plasma growth hormone triggers tyrosine phosphorylation and nuclear translocation of a liver-expressed, Stat 5-related DNA binding protein. Proposed role as an intracellular regulator of male-specific liver gene transcription

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Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression

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Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses

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STAT5b-deficient mice are growth hormone pulse-resistant. Role of STAT5b in sex-specific liver p450 expression.

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Phosphorylation of Raf-1 serine 338-serine 339 is an essential regulatory event for Ras-dependent activation and biological signaling

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Prolonged insulin treatment inhibits GH signaling via STAT3 and STAT1

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Insulin inhibits growth hormone signaling via the growth hormone receptor/JAK2/STAT5B pathway

21 January 2018

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Insulin enhances growth hormone induction of the MEK/ERK signaling pathway

21 January 2018

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Growth allometry of the organs in giant transgenic mice

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Accelerated growth and visceral lesions in transgenic mice expressing foreign genes of the growth hormone family: an overview

21 January 2018

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KSR stimulates Raf-1 activity in a kinase-independent manner

21 January 2018

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C-TAK1 regulates Ras signaling by phosphorylating the MAPK scaffold, KSR1

21 January 2018

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Kinase suppressor of Ras forms a multiprotein signaling complex and modulates MEK localization

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The protein kinase KSR interacts with 14-3-3 protein and Raf.

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Signal transduction: implications for Ras-dependent ERK signaling.

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Interpulse growth hormone secretion in the episodic plasma profile causes the sex reversal of cytochrome P450s in senescent male rats

21 January 2018

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Divergent mechanisms for homologous desensitization of p21ras by insulin and growth factors

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The role of STAT proteins in growth hormone signaling

21 January 2018

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Activation of acute phase response factor (APRF)/Stat3 transcription factor by growth hormone.

21 January 2018

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Identification of growth hormone receptor (GHR) tyrosine residues required for GHR phosphorylation and JAK2 and STAT5 activation

21 January 2018

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The role of the growth hormone (GH) receptor and JAK1 and JAK2 kinases in the activation of Stats 1, 3, and 5 by GH.

21 January 2018

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The membrane proximal region of the cytoplasmic domain of the growth hormone receptor is involved in the activation of Stat 3

21 January 2018

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Intracellular tyrosine residues of the human growth hormone receptor are not required for the signaling of proliferation or Jak-STAT activation

21 January 2018

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A novel C-terminal growth hormone receptor (GHR) mutation results in impaired GHR-STAT5 but normal STAT-3 signaling

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Growth hormone preferentially induces the rapid, transient expression of SOCS-3, a novel inhibitor of cytokine receptor signaling

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SOCS/CIS protein inhibition of growth hormone-stimulated STAT5 signaling by multiple mechanisms

21 January 2018

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SOCS proteins: negative regulators of cytokine signaling

21 January 2018

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Direct association with and dephosphorylation of Jak2 kinase by the SH2-domain-containing protein tyrosine phosphatase SHP-1

21 January 2018

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A novel, testis-specific mRNA transcript encoding an NH2-terminal truncated nitric-oxide synthase

21 January 2018

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Growth hormone regulation of SIRP and SHP-2 tyrosyl phosphorylation and association

21 January 2018

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Involvement of the Src homology 2-containing tyrosine phosphatase SHP-2 in growth hormone signaling

21 January 2018

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Negative regulation of growth hormone receptor/JAK2 signaling by signal regulatory protein alpha

21 January 2018

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Inadequacy of the Janus kinase 2/signal transducer and activator of transcription signal transduction pathway to mediate episodic growth hormone-dependent regulation of hepatic CYP2C11.

21 January 2018

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Role of growth hormone (GH) in liver regeneration

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Secular trends in growth in diabetes: are we winning?

21 January 2018

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Essential role of STAT3 in the control of the acute-phase response as revealed by inducible gene inactivation [correction of activation] in the liver

21 January 2018

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Cytokine-inducible enhancer with promoter activity in both the rat and human manganese-superoxide dismutase genes

21 January 2018

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Identification of hemopexin as a GH-regulated gene

21 January 2018

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Kinase suppressor of Ras (KSR) is a scaffold which facilitates mitogen-activated protein kinase activation in vivo

21 January 2018

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Pseudoexon activation as a novel mechanism for disease resulting in atypical growth-hormone insensitivity

21 January 2018

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A novel dysfunctional growth hormone variant (Ile179Met) exhibits a decreased ability to activate the extracellular signal-regulated kinase pathway

21 January 2018

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Assessment of growth parameters and life span of GHR/BP gene-disrupted mice.

21 January 2018

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In vivo analysis of growth hormone receptor signaling domains and their associated transcripts

21 January 2018

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Differential Activation of Acute Phase Response Factor/STAT3 and STAT1 via the Cytoplasmic Domain of the Interleukin 6 Signal Transducer gp130

21 January 2018

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Growth hormone-induced differential desensitization of STAT5, ERK, and Akt phosphorylation

21 January 2018

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High, persistent hepatocellular proliferation and apoptosis precede hepatocarcinogenesis in growth hormone transgenic mice

21 January 2018

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Identification of tyrosine residues in the intracellular domain of the growth hormone receptor required for transcriptional signaling and Stat5 activation

21 January 2018

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The Mauriac syndrome: dwarfism, hepatomegaly and obesity with juvenile diabetes mellitus

21 January 2018

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Growth hormone attenuates the acute-phase response to thermal injury

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M513612200

1 reference

16 May 2018

1 reference

16 May 2018