HSP110-HER2/neu Chaperone Complex Vaccine Induces Protective Immunity Against Spontaneous Mammary Tumors in HER-2/neu Transgenic Mice (Q53649926)

16 May 2018

title

HSP110-HER2/neu Chaperone Complex Vaccine Induces Protective Immunity Against Spontaneous Mammary Tumors in HER-2/neu Transgenic Mice (English)

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https://api.crossref.org/works/10.4049/JIMMUNOL.171.8.4054

18 March 2024

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https://api.crossref.org/works/10.4049/JIMMUNOL.171.8.4054

18 March 2024

author name string

Xiang-Yang Wang

2

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16 May 2018

Xing Chen

3

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16 May 2018

Thomas Martin

4

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16 May 2018

Robert Henderson

6

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16 May 2018

Masoud H. Manjili

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14530326

18 March 2024

Elizabeth A. Repasky

5

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14530326

18 March 2024

John R. Subjeck

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14530326

18 March 2024

language of work or name

English

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publication date

1 October 2003

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16 May 2018

15 October 2003

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14530326

18 March 2024

published in

Journal of Immunology

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16 May 2018

volume

171

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16 May 2018

issue

8

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16 May 2018

page(s)

4054-4061

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16 May 2018

Calreticulin, a peptide-binding chaperone of the endoplasmic reticulum, elicits tumor- and peptide-specific immunity

cites work

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Immunotherapy of tumors with autologous tumor-derived heat shock protein preparations

18 March 2024

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Characterization of heat shock protein 110 and glucose-regulated protein 170 as cancer vaccines and the effect of fever-range hyperthermia on vaccine activity

18 March 2024

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https://api.crossref.org/works/10.4049/JIMMUNOL.171.8.4054

Roles of heat-shock proteins in innate and adaptive immunity

18 March 2024

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1 reference

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HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine

18 March 2024

7

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.8.4054

Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex

18 March 2024

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Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4.

18 March 2024

9

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The endoplasmic reticulum-resident heat shock protein Gp96 activates dendritic cells via the Toll-like receptor 2/4 pathway

18 March 2024

10

1 reference

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Receptor-mediated uptake of antigen/heat shock protein complexes results in major histocompatibility complex class I antigen presentation via two distinct processing pathways

18 March 2024

11

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.8.4054

Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-kappa B pathway

18 March 2024

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The role of heat shock protein (hsp70) in dendritic cell maturation: hsp70 induces the maturation of immature dendritic cells but reduces DC differentiation from monocyte precursors

18 March 2024

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1 reference

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Hsp110 protects heat-denatured proteins and confers cellular thermoresistance.

18 March 2024

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Immunization with a HER-2/neu helper peptide vaccine generates HER-2/neu CD8 T-cell immunity in cancer patients

18 March 2024

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1 reference

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Generation of T-cell immunity to the HER-2/neu protein after active immunization with HER-2/neu peptide-based vaccines

18 March 2024

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Clonal diversity of the T-cell population responding to a dominant HLA-A2 epitope of HER-2/neu after active immunization in an ovarian cancer patient

18 March 2024

20

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Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease

18 March 2024

21

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Prevention of spontaneous neu-expressing mammary tumor development in mice transgenic for rat proto-neu by DNA vaccination.

18 March 2024

22

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HER-2/neu protein: a target for antigen-specific immunotherapy of human cancer.

18 March 2024

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Human HER-2/neu protein immunization circumvents tolerance to rat neu: a vaccine strategy for 'self' tumour antigens

18 March 2024

25

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Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma

18 March 2024

26

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Enhancement of antigen-presenting cell surface molecules involved in cognate interactions by immunostimulatory DNA sequences

18 March 2024

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1 reference

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Vaccination with cytoplasmic ErbB-2 DNA protects mice from mammary tumor growth without anti-ErbB-2 antibody

18 March 2024

29

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Combined allogeneic tumor cell vaccination and systemic interleukin 12 prevents mammary carcinogenesis in HER-2/neu transgenic mice

18 March 2024

30

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Functional avidity maturation of CD8(+) T cells without selection of higher affinity TCR

18 March 2024

32

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Heat shock protein-peptide complexes elicit cytotoxic T-lymphocyte and antibody responses specific for bovine herpesvirus 1.

18 March 2024

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Cutting edge: control of CD8+ T cell activation by CD4+CD25+ immunoregulatory cells

18 March 2024

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Do CD4+ CD25+ immunoregulatory T cells hinder tumor immunotherapy?

18 March 2024

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Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

18 March 2024

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1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.8.4054

Phenotype, localization, and mechanism of suppression of CD4(+)CD25(+) human thymocytes

18 March 2024

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https://api.crossref.org/works/10.4049/JIMMUNOL.171.8.4054

Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance

18 March 2024

40

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.8.4054

18 March 2024

Identifiers

1 reference

16 May 2018

1 reference

16 May 2018