Genetic background determines the extent of islet amyloid formation in human islet amyloid polypeptide transgenic mice. (Q53856651)

21 May 2018

title

Genetic background determines the extent of islet amyloid formation in human islet amyloid polypeptide transgenic mice. (English)

1 reference

21 May 2018

author

Steven E. Kahn

8

1 reference

21 May 2018

author name string

Rebecca L Hull

1

1 reference

21 May 2018

Melissah R Watts

2

1 reference

21 May 2018

Keiichi Kodama

3

1 reference

21 May 2018

Zhen-ping Shen

4

1 reference

21 May 2018

Kristina M Utzschneider

5

1 reference

21 May 2018

Darcy B Carr

6

1 reference

21 May 2018

Josep Vidal

7

1 reference

21 May 2018

publication date

17 May 2005

1 reference

21 May 2018

American Journal of Physiology - Endocrinology and Metabolism

published in

1 reference

21 May 2018

volume

289

1 reference

21 May 2018

issue

4

1 reference

21 May 2018

page(s)

E703-9

1 reference

21 May 2018

Reducing plasma free fatty acids by acipimox improves glucose tolerance in high-fat fed mice

cites work

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00471.2004

beta-cell glucokinase deficiency and hyperglycemia are associated with reduced islet amyloid deposition in a mouse model of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00471.2004

Genetic background determines the size and structure of the endocrine pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00471.2004

Visceral adiposity and risk of type 2 diabetes: a prospective study among Japanese Americans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00471.2004

Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00471.2004

The influence of genetic background on the expression of the obese (ob) gene in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00471.2004

Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00471.2004

Pancreatic expression and secretion of human islet amyloid polypeptide in a transgenic mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00471.2004

Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00471.2004

Human islet amyloid polypeptide transgenic mice as a model of non-insulin-dependent diabetes mellitus (NIDDM).

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00471.2004

Glucose homeostasis and tissue transcript content of insulin signaling intermediates in four inbred strains of mice: C57BL/6, C57BLKS/6, DBA/2, and 129X1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00471.2004

Genetic background (C57BL/6J versus FVB/N) strongly influences the severity of diabetes and insulin resistance in ob/ob mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00471.2004

Family and genetic studies of indices of insulin sensitivity and insulin secretion in Pima Indians

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00471.2004

Extensive islet amyloid formation is induced by development of Type II diabetes mellitus and contributes to its progression: pathogenesis of diabetes in a mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00471.2004

Chronic overproduction of islet amyloid polypeptide/amylin in transgenic mice: lysosomal localization of human islet amyloid polypeptide and lack of marked hyperglycaemia or hyperinsulinaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00471.2004

Increased dietary fat promotes islet amyloid formation and beta-cell secretory dysfunction in a transgenic mouse model of islet amyloid

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00471.2004

Dietary-fat-induced obesity in mice results in beta cell hyperplasia but not increased insulin release: evidence for specificity of impaired beta cell adaptation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00471.2004

Long-term treatment with rosiglitazone and metformin reduces the extent of, but does not prevent, islet amyloid deposition in mice expressing the gene for human islet amyloid polypeptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00471.2004

Spontaneous diabetes mellitus in transgenic mice expressing human islet amyloid polypeptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00471.2004

Reduced amylin release is a characteristic of impaired glucose tolerance and type 2 diabetes in Japanese Americans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00471.2004

Diabetes incidence and prevalence in Pima Indians: a 19-fold greater incidence than in Rochester, Minnesota

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00471.2004

Insulin and amylin release are both diminished in first-degree relatives of subjects with type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00471.2004

Impact of genetic background on development of hyperinsulinemia and diabetes in insulin receptor/insulin receptor substrate-1 double heterozygous mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00471.2004

In vivo insulin action is familial characteristic in nondiabetic Pima Indians

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00471.2004

Contribution to glucose tolerance of insulin-independent vs. insulin-dependent mechanisms in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00471.2004

Variation in type 2 diabetes--related traits in mouse strains susceptible to diet-induced obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00471.2004

Islet amyloid-associated diabetes in obese A(vy)/a mice expressing human islet amyloid polypeptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00471.2004

Diet-induced type II diabetes in C57BL/6J mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00471.2004

A genetic and physiological study of impaired glucose homeostasis control in C57BL/6J mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00471.2004

Islet amyloid formation associated with hyperglycemia in transgenic mice with pancreatic beta cell expression of human islet amyloid polypeptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00471.2004

Islet amyloid develops diffusely throughout the pancreas before becoming severe and replacing endocrine cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00471.2004

Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00471.2004

Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islet cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00471.2004

10.1152/AJPENDO.00471.2004

21 January 2018

Identifiers

DOI

1 reference

21 May 2018

PubMed ID

15899941

1 reference

21 May 2018