Interferon-gamma mRNA attenuates its own translation by activating PKR: a molecular basis for the therapeutic effect of interferon-beta in multiple sclerosis. (Q53924474)

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English	Interferon-gamma mRNA attenuates its own translation by activating PKR: a molecular basis for the therapeutic effect of interferon-beta in multiple sclerosis.	scientific article

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scholarly article

1 reference

Europe PubMed Central

22 May 2018

http://europepmc.org/abstract/MED/16474427

Interferon-gamma mRNA attenuates its own translation by activating PKR: a molecular basis for the therapeutic effect of interferon-beta in multiple sclerosis. (English)

1 reference

Europe PubMed Central

22 May 2018

http://europepmc.org/abstract/MED/16474427

multiple sclerosis

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author name string

Raymond Kaempfer

1

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Europe PubMed Central

22 May 2018

http://europepmc.org/abstract/MED/16474427

publication date

1 February 2006

1 reference

Europe PubMed Central

22 May 2018

http://europepmc.org/abstract/MED/16474427

1 reference

Europe PubMed Central

22 May 2018

http://europepmc.org/abstract/MED/16474427

16

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Europe PubMed Central

22 May 2018

http://europepmc.org/abstract/MED/16474427

2

1 reference

Europe PubMed Central

22 May 2018

http://europepmc.org/abstract/MED/16474427

148-153

1 reference

Europe PubMed Central

22 May 2018

http://europepmc.org/abstract/MED/16474427

https://scigraph.springernature.com/pub.10.1038/sj.cr.7310020

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Human interferon-gamma mRNA autoregulates its translation through a pseudoknot that activates the interferon-inducible protein kinase PKR

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7310020

21 January 2018

Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7310020

21 January 2018

How cells respond to interferons

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https://api.crossref.org/works/10.1038%2FSJ.CR.7310020

21 January 2018

Minor-groove recognition of double-stranded RNA by the double-stranded RNA-binding domain from the RNA-activated protein kinase PKR.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7310020

21 January 2018

A cis-acting element in the 3'-untranslated region of human TNF-alpha mRNA renders splicing dependent on the activation of protein kinase PKR.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7310020

21 January 2018

RNA sensors: novel regulators of gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7310020

21 January 2018

Hyperinducible expression of the interferon-gamma (IFN-gamma) gene and its suppression in systemic lupus erythematosus (SLE).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7310020

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The gamma134.5 protein of herpes simplex virus 1 has the structural and functional attributes of a protein phosphatase 1 regulatory subunit and is present in a high molecular weight complex with the enzyme in infected cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7310020

21 January 2018

Exacerbations of multiple sclerosis in patients treated with gamma interferon

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7310020

21 January 2018

Interferon (IFN)-beta 1a and IFN-beta 1b block IFN-gamma-induced disintegration of endothelial junction integrity and barrier.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7310020

21 January 2018

Interferon-β treatment in multiple sclerosis patients decreases the number of circulating T cells producing interferon-γ and interleukin-4

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7310020

21 January 2018

Mechanism of interferon action: evidence for intermolecular autophosphorylation and autoactivation of the interferon-induced, RNA-dependent protein kinase PKR

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7310020

7 January 2021

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Seasonal variation of interferon-gamma production in progressive multiple sclerosis

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7 January 2021

based on heuristic

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IL-18 is linked to raised IFN-gamma in multiple sclerosis and is induced by activated CD4(+) T cells via CD40-CD40 ligand interactions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7310020

7 January 2021

based on heuristic

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Association between peripheral IFN-γ producing CD8+ T-cells and disability score in relapsing-remitting multiple sclerosis

1 reference

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7 January 2021

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Superantigen antagonist protects against lethal shock and defines a new domain for T-cell activation

1 reference

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7 January 2021

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Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. I. Clinical results of a multicenter, randomized, double-blind, placebo-controlled trial. The IFNB Multiple Sclerosis Study Group

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7310020

7 January 2021

based on heuristic

inferred from DOI database lookup

Correlation between interferon production and clinical disease activity in patients with multiple sclerosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7310020

7 January 2021

based on heuristic

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Cytokine mRNA expression in inflammatory multiple sclerosis lesions: detection by non-radioactive in situ hybridization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7310020

7 January 2021

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Identifiers

10.1038/SJ.CR.7310020

1 reference

Europe PubMed Central

22 May 2018

http://europepmc.org/abstract/MED/16474427

1 reference

Europe PubMed Central

22 May 2018

http://europepmc.org/abstract/MED/16474427

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