Prolonged IFN-gamma-producing NKT response induced with alpha-galactosylceramide-loaded DCs. (Q53963043)

23 May 2018

title

Prolonged IFN-gamma-producing NKT response induced with alpha-galactosylceramide-loaded DCs. (English)

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23 May 2018

3

Mitchell Kronenberg

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23 May 2018

4

Ralph M Steinman

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23 May 2018

author name string

Shin-ichiro Fujii

series ordinal

1

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23 May 2018

Kanako Shimizu

series ordinal

2

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23 May 2018

language of work or name

English

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publication date

5 August 2002

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23 May 2018

published in

Nature Immunology

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23 May 2018

volume

3

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23 May 2018

page(s)

867-874

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23 May 2018

issue

9

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23 May 2018

Mouse CD1-specific NK1 T cells: development, specificity, and function

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CD1-restricted NK T cells protect nonobese diabetic mice from developing diabetes

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Activation of natural killer T cells potentiates or prevents experimental autoimmune encephalomyelitis

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Natural killer T cell activation protects mice against experimental autoimmune encephalomyelitis.

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Natural killer-like nonspecific tumor cell lysis mediated by specific ligand-activated Valpha14 NKT cells

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Inhibition of tumor metastasis by adoptive transfer of IL-12-activated Valpha14 NKT cells

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Mechanisms of the antimetastatic effect in the liver and of the hepatocyte injury induced by alpha-galactosylceramide in mice

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alpha -galactosylceramide-activated Valpha 14 natural killer T cells mediate protection against murine malaria

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CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides

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CD1d-mediated recognition of an alpha-galactosylceramide by natural killer T cells is highly conserved through mammalian evolution

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CD1d-restricted recognition of synthetic glycolipid antigens by human natural killer T cells

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Presentation of self and microbial lipids by CD1 molecules

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Crystal structure of mouse CD1: An MHC-like fold with a large hydrophobic binding groove

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In vivo identification of glycolipid antigen-specific T cells using fluorescent CD1d tetramers

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Tracking the response of natural killer T cells to a glycolipid antigen using CD1d tetramers

21 January 2018

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The natural killer T (NKT) cell ligand alpha-galactosylceramide demonstrates its immunopotentiating effect by inducing interleukin (IL)-12 production by dendritic cells and IL-12 receptor expression on NKT cells

21 January 2018

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CD1d on myeloid dendritic cells stimulates cytokine secretion from and cytolytic activity of V alpha 24J alpha Q T cells: a feedback mechanism for immune regulation

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Distinct cytokine profiles of neonatal natural killer T cells after expansion with subsets of dendritic cells

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Analysis of human V alpha 24+ CD4+ NKT cells activated by alpha-glycosylceramide-pulsed monocyte-derived dendritic cells

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Dendritic cells pulsed with protein antigens in vitro can prime antigen-specific, MHC-restricted T cells in situ

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Selective Expansion and Partial Activation of Human NK Cells and NK Receptor-Positive T Cells by IL-2 and IL-15

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The natural killer T-cell ligand α-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice

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7 January 2021

Activation of natural killer T cells by alpha-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes

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7 January 2021

Costimulation-dependent modulation of experimental autoimmune encephalomyelitis by ligand stimulation of V alpha 14 NK T cells

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Sequential production of interferon-gamma by NK1.1+ T cells and natural killer cells is essential for the antimetastatic effect of alpha -galactosylceramide

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7 January 2021

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7 January 2021

Activating immunity in the liver. I. Liver dendritic cells (but not hepatocytes) are potent activators of IFN-gamma release by liver NKT cells

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The interface between innate and acquired immunity: glycolipid antigen presentation by CD1d-expressing dendritic cells to NKT cells induces the differentiation of antigen-specific cytotoxic T lymphocytes

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7 January 2021

Rapid Death and Regeneration of NKT Cells in Anti-CD3ε- or IL-12-Treated Mice

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7 January 2021

Activation of hepatic NKT cells and subsequent liver injury following administration of α-galactosylceramide

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7 January 2021

Critical contribution of IFN-γ and NK cells, but not perforin-mediated cytotoxicity, to anti-metastatic effect of α-galactosylceramide

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7 January 2021

Fetal calf serum-free generation of functionally active murine dendritic cells suitable for in vivo therapeutic approaches

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7 January 2021

Potentiation of antitumor effect of NKT cell ligand, alpha-galactosylceramide by combination with IL-12 on lung metastasis of malignant melanoma cells

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7 January 2021

Identifiers

DOI

10.1038/NI827

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23 May 2018

PubMed ID

12154358

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23 May 2018