Normal structure of NFKB2, C-REL and BCL-3 gene loci in lymphoproliferative and myeloproliferative disorders. (Q54050091)

24 May 2018

title

Normal structure of NFKB2, C-REL and BCL-3 gene loci in lymphoproliferative and myeloproliferative disorders. (English)

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24 May 2018

author name string

Munzert G

series ordinal

1

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24 May 2018

Kreitmeier S

series ordinal

2

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24 May 2018

Bergmann L

series ordinal

3

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24 May 2018

publication date

1 July 2000

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24 May 2018

published in

Leukemia & Lymphoma

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24 May 2018

volume

38

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24 May 2018

issue

3-4

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24 May 2018

page(s)

395-400

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24 May 2018

Function and activation of NF-kappa B in the immune system

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Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses

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Nuclear factor (NF)-kappa B2 (p100/p52) is required for normal splenic microarchitecture and B cell-mediated immune responses

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Mice deficient in nuclear factor (NF)-kappa B/p52 present with defects in humoral responses, germinal center reactions, and splenic microarchitecture

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Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-kappa B/Rel family

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p50-NF-kappaB complexes partially compensate for the absence of RelB: severely increased pathology in p50(-/-)relB(-/-) double-knockout mice

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B cell lymphoma-associated chromosomal translocation involves candidate oncogene lyt-10, homologous to NF-kappa B p50

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Cloning of the chromosome translocation breakpoint junction of the t(14;19) in chronic lymphocytic leukemia

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The proto-oncogene bcl-3 encodes an I kappa B protein

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The oncoprotein Bcl-3 directly transactivates through kappa B motifs via association with DNA-binding p50B homodimers

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Genomic structure of the candidate proto-oncogene BCL3.

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Constitutive expression of lymphoma-associated NFKB-2/Lyt-10 proteins is tumorigenic in murine fibroblasts

21 January 2018

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Rearranged NFKB-2 Genes in Lymphoid Neoplasms Code for Constitutively Active Nuclear Transactivators

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Transcriptional regulation of NF-kappa B2: evidence for kappa B-mediated positive and negative autoregulation

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Genetic characterization of human c-rel sequences

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10.3109/10428190009087031

21 January 2018

Identifiers

DOI

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24 May 2018

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24 May 2018