Mutational analysis of active-site residues of the enterococcal D-ala-D-Ala dipeptidase VanX and comparison with Escherichia coli D-ala-D-Ala ligase and D-ala-D-Ala carboxypeptidase VanY. (Q54102921)

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English	Mutational analysis of active-site residues of the enterococcal D-ala-D-Ala dipeptidase VanX and comparison with Escherichia coli D-ala-D-Ala ligase and D-ala-D-Ala carboxypeptidase VanY.	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

24 May 2018

http://europepmc.org/abstract/MED/10074467

Mutational analysis of active-site residues of the enterococcal D-ala-D-Ala dipeptidase VanX and comparison with Escherichia coli D-ala-D-Ala ligase and D-ala-D-Ala carboxypeptidase VanY. (English)

1 reference

Europe PubMed Central

24 May 2018

http://europepmc.org/abstract/MED/10074467

mutational analysis

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based on heuristic

inferred from title

Escherichia coli

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author name string

Lessard IA

1

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Europe PubMed Central

24 May 2018

http://europepmc.org/abstract/MED/10074467

Walsh CT

2

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Europe PubMed Central

24 May 2018

http://europepmc.org/abstract/MED/10074467

publication date

1 March 1999

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Europe PubMed Central

24 May 2018

http://europepmc.org/abstract/MED/10074467

Chemistry and Biology

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Europe PubMed Central

24 May 2018

http://europepmc.org/abstract/MED/10074467

6

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Europe PubMed Central

24 May 2018

http://europepmc.org/abstract/MED/10074467

3

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Europe PubMed Central

24 May 2018

http://europepmc.org/abstract/MED/10074467

177-187

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Europe PubMed Central

24 May 2018

http://europepmc.org/abstract/MED/10074467

The crisis in antibiotic resistance

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Multiple-Antibiotic-Resistant Pathogenic Bacteria -- A Report on the Rockefeller University Workshop

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7 January 2021

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Historical yearly usage of vancomycin.

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7 January 2021

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Resistance to glycopeptides in enterococci

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7 January 2021

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Vancomycin-resistant enterococci

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7 January 2021

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7 January 2021

based on heuristic

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Genetics and mechanisms of glycopeptide resistance in enterococci

1 reference

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Characterization of Tn1546, a Tn3-related transposon conferring glycopeptide resistance by synthesis of depsipeptide peptidoglycan precursors in Enterococcus faecium BM4147.

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Bacterial resistance to vancomycin: five genes and one missing hydrogen bond tell the story

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Molecular basis for vancomycin resistance in Enterococcus faecium BM4147: biosynthesis of a depsipeptide peptidoglycan precursor by vancomycin resistance proteins VanH and VanA.

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7 January 2021

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The VanS-VanR two-component regulatory system controls synthesis of depsipeptide peptidoglycan precursors in Enterococcus faecium BM4147

1 reference

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7 January 2021

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Glycopeptide resistance mediated by enterococcal transposon Tn1546 requires production of VanX for hydrolysis of D-alanyl-D-alanine.

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Overexpression, purification, and characterization of VanX, a D-, D-dipeptidase which is essential for vancomycin resistance in Enterococcus faecium BM4147.

1 reference

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based on heuristic

inferred from DOI database lookup

Control of peptidoglycan synthesis in vancomycin-resistant enterococci: D,D-peptidases and D,D-carboxypeptidases.

1 reference

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7 January 2021

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Glycopeptide antibiotic resistance genes in glycopeptide-producing organisms

1 reference

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7 January 2021

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Homologs of the vancomycin resistance D-Ala-D-Ala dipeptidase VanX in Streptomyces toyocaensis, Escherichia coli and Synechocystis: attributes of catalytic efficiency, stereoselectivity and regulation with implications for function.

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The glycopeptide antibiotic producer Streptomyces toyocaensis NRRL 15009 has both ?-alanyl-?-alanine and ?-alanyl-?-lactate ligases

1 reference

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7 January 2021

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The structure of VanX reveals a novel amino-dipeptidase involved in mediating transposon-based vancomycin resistance

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7 January 2021

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Vancomycin resistance: structure of D-alanine:D-alanine ligase at 2.3 A resolution

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Structure of a Zn2+-containing D-alanyl-D-alanine-cleaving carboxypeptidase at 2.5 A resolution

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Mutational analysis of potential zinc-binding residues in the active site of the enterococcal D-Ala-D-Ala dipeptidase VanX.

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Gain of D-alanyl-D-lactate or D-lactyl-D-alanine synthetase activities in three active-site mutants of the Escherichia coli D-alanyl-D-alanine ligase B

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Active site mapping of Escherichia coli D-Ala-D-Ala ligase by structure-based mutagenesis

1 reference

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7 January 2021

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Characterization of vanY, a DD-carboxypeptidase from vancomycin-resistant Enterococcus faecium BM4147.

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Identifiers

10.1016/S1074-5521(99)89009-7

1 reference

Europe PubMed Central

24 May 2018

http://europepmc.org/abstract/MED/10074467

1 reference

Europe PubMed Central

24 May 2018

http://europepmc.org/abstract/MED/10074467

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