Inhibitory function of two NFAT family members in lymphoid homeostasis and Th2 development. (Q54113549)

24 May 2018

title

Inhibitory function of two NFAT family members in lymphoid homeostasis and Th2 development. (English)

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24 May 2018

4

Glimcher LH

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24 May 2018

author name string

Ranger AM

series ordinal

1

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24 May 2018

Oukka M

series ordinal

2

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24 May 2018

Rengarajan J

series ordinal

3

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24 May 2018

language of work or name

English

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publication date

1 November 1998

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24 May 2018

published in

Immunity

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24 May 2018

volume

9

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24 May 2018

issue

5

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24 May 2018

page(s)

627-635

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24 May 2018

Nuclear localization of NF-ATc by a calcineurin-dependent, cyclosporin-sensitive intramolecular interaction

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Multiple closely-linked NFAT/octamer and HMG I(Y) binding sites are part of the interleukin-4 promoter

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Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

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Human granulocyte-macrophage colony-stimulating factor enhancer function is associated with cooperative interactions between AP-1 and NFATp/c

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Purified protein derivative of Mycobacterium tuberculosis and excretory-secretory antigen(s) of Toxocara canis expand in vitro human T cells with stable and opposite (type 1 T helper or type 2 T helper) profile of cytokine production

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Cyclosporin A specifically inhibits function of nuclear proteins involved in T cell activation

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Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A

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Identification of a novel cyclosporin-sensitive element in the human tumor necrosis factor alpha gene promoter

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NFATc3, a lymphoid-specific NFATc family member that is calcium-regulated and exhibits distinct DNA binding specificity

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Hyperproliferation and dysregulation of IL-4 expression in NF-ATp-deficient mice

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Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins

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Nuclear factor of activated T cells contains Fos and Jun.

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The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun

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Down-regulation of IL-4 gene transcription and control of Th2 cell differentiation by a mechanism involving NFAT1

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The T cell activation factor NF-ATc positively regulates HIV-1 replication and gene expression in T cells

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Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum

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The granulocyte-macrophage colony-stimulating factor promoter cis-acting element CLE0 mediates induction signals in T cells and is recognized by factors related to AP1 and NFAT.

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NFATx, a novel member of the nuclear factor of activated T cells family that is expressed predominantly in the thymus

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Isolation of the cyclosporin-sensitive T cell transcription factor NFATp

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Characterization of the mouse granulocyte-macrophage colony-stimulating factor (GM-CSF) gene promoter: nuclear factors that interact with an element shared by three lymphokine genes--those for GM-CSF, interleukin-4 (IL-4), and IL-5.

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7 January 2021

NF-AT components define a family of transcription factors targeted in T-cell activation

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7 January 2021

The transcription factor NFAT4 is involved in the generation and survival of T cells

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7 January 2021

The transcription factor NF-ATc is essential for cardiac valve formation

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Delayed lymphoid repopulation with defects in IL-4-driven responses produced by inactivation of NF-ATc

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Transcription factors of the NFAT family: regulation and function

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Novel NFAT sites that mediate activation of the interleukin-2 promoter in response to T-cell receptor stimulation

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7 January 2021

Coordinate and cooperative roles for NF-AT and AP-1 in the regulation of the murine IL-4 gene

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7 January 2021

Generalized autoimmune disease in interleukin-2-deficient mice is triggered by an uncontrolled activation and proliferation of CD4+ T cells

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7 January 2021

Identification of a putative regulator of early T cell activation genes

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7 January 2021

Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand

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7 January 2021

IL-4 induces allergic-like inflammatory disease and alters T cell development in transgenic mice.

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7 January 2021

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

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7 January 2021

Structure of the murine CD40 ligand gene

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7 January 2021

Cyclosporin-A sensitive induction of NF-AT in murine B cells

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Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

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Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment

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Cytokine regulation of granuloma formation in schistosomiasis

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7 January 2021

An enhanced immune response in mice lacking the transcription factor NFAT1.

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7 January 2021

The transcription factor NF-ATc1 regulates lymphocyte proliferation and Th2 cytokine production

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7 January 2021

The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells

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7 January 2021

10.1016/S1074-7613(00)80660-3

Identifiers

DOI

1 reference

24 May 2018

1 reference

24 May 2018